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Rates* of reported cases† of acute Hepatitis B virus infection, by age group — United States, 2006–2021
* Rates per 100,000 population. Beginning in 2021, single-race population estimates are used for rate calculations. For prior years, bridged-race population estimates are used.
† Reported confirmed cases. For the case definition, see Acute Hepatitis B.
Since 2011, rates of reported cases of acute hepatitis B remained low and decreased among children and adolescents aged 0–19 years and persons aged 20–29 years. This is likely explained, in part, because of the implementation of childhood hepatitis B vaccine recommendations first published in 1991. As the cohort of persons vaccinated as children have grown older, rates of acute hepatitis B among persons aged 30–39 years began to consistently decrease beginning in 2015.
Conversely, rates of reported cases of acute hepatitis B have steadily increased among persons aged 40–49, 50–59 years, and 60 years and older from 2015–2019. In 2020, rates declined in all adult age groups. In 2021, rates among all age groups remain stable or declined compared to 2020. The highest rates were among persons 40–49 years (1.6 cases per 100,000 population) and 50–59 years (1.0 case per 100,000 population).
- Figure 2.1. Number of reported cases of acute hepatitis B virus infection and estimated infections — United States, 2014–2021
- Figure 2.2. Rates of reported acute hepatitis B virus infection, by state or jurisdiction — United States, 2020–2021
- Figure 2.3. Rates of reported cases of acute hepatitis B virus infection, by state or jurisdiction — United States, 2021
- Figure 2.4. Rates of reported cases of acute hepatitis B virus infection, by age group — United States, 2006–2021
- Figure 2.5. Rates of reported cases of acute hepatitis B virus infection, by sex — United States, 2006–2021
- Figure 2.6. Rates of reported cases of acute hepatitis B virus infection, by race/ethnicity — United States, 2006–2021
- Figure 2.7. Availability of information on risk behaviors or exposures associated with reported cases of acute hepatitis B virus infection — United States, 2021
- Figure 2.8. Rates of deaths with hepatitis B virus infection listed as a cause of death among residents, by state or jurisdiction — United States, 2021
- Table 2.1. Numbers and rates of reported cases of acute hepatitis B virus infection, by state or jurisdiction — United States, 2017–2021
- Table 2.2. Numbers and rates of reported cases of acute hepatitis B virus infection, by demographic characteristics — United States, 2017–2021
- Table 2.3. Reported risk behaviors or exposures among reported cases of acute hepatitis B virus infection — United States, 2021
- Table 2.4. Number of newly reported cases of perinatal hepatitis B virus infection, by state or jurisdiction — United States, 2021
- Table 2.5. Number and rate of newly reported cases of chronic hepatitis B virus infection, by state or jurisdiction — United States, 2021
- Table 2.6. Number and rate of newly reported cases of chronic hepatitis B virus infection, by demographic characteristics — United States, 2021
- Table 2.7. Numbers and rates of deaths with hepatitis B virus infection listed as a cause of death among residents, by state or jurisdiction — United States, 2017–2021
- Table 2.8. Numbers and rates of deaths with hepatitis B virus infections listed as a cause of death among residents, by demographic characteristics — United States, 2017–2021