Table 1.2. Number and rates* of reported cases† of hepatitis A virus infection, by demographic characteristics — United States 2015–2019

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Table 1.3 ▶
Table 1.2 Number and rates* of reported cases† of hepatitis A virus infection, by demographic characteristics — United States 2015–2019
Table 2.2.
Characteristics 2015 No. 2015 Rate* 2016 No. 2016 Rate* 2017 No. 2017 Rate* 2018 No. 2018 Rate* 2019 No. 2019 Rate*
Total§ 1,390 0.4 2,007 0.6 3,366 1.0 12,474 3.8 18,846 5.7
Age (years)
0-9 48 0.1 47 0.1 40 0.1 54 0.1 127 0.3
10-19 97 0.2 131 0.3 86 0.2 231 0.6 231 0.6
20-29 287 0.6 392 0.9 659 1.4 2,763 6.1 3,582 7.9
30-39 233 0.6 391 0.9 893 2.1 4,268 9.8 6,400 14.5
40-49 164 0.4 333 0.8 621 1.5 2,658 6.6 4,177 10.4
50-59 205 0.5 297 0.7 554 1.3 1,509 3.5 2,635 6.2
≥60 353 0.5 409 0.6 509 0.7 987 1.4 1,691 2.3
Sex
Male 726 0.5 1,107 0.7 2,209 1.4 7,497 4.7 11,824 7.3
Female 662 0.4 897 0.5 1,149 0.7 4,952 3.0 6,997 4.2
Race/ethnicity
American Indian/Alaska Native 5 0.2 3 0.1 13 0.5 15 0.5 60 2.2
Asian/Pacific Islander 114 0.6 299 1.5 124 0.6 104 0.5 139 0.7
Black, non-Hispanic 71 0.2 137 0.3 303 0.7 508 1.2 1,072 2.5
White, non-Hispanic 701 0.3 865 0.4 1,979 1.0 8,670 4.3 13,709 6.8
Hispanic 219 0.4 293 0.5 471 0.8 413 0.7 916 1.5
Urbanicity
Urban 1,198 0.4 1,769 0.6 3,055 1.1 7,657 2.7 14,637 5.2
Rural 181 0.4 182 0.4 180 0.4 3,153 6.8 3,372 7.3
HHS Region#
Region 1: Boston 60 0.4 105 0.7 91 0.6 410 2.8 593 4.0
Region 2: New York 182 0.6 173 0.6 289 1.0 235 0.8 1,001 3.5
Region 3: Philadelphia 122 0.4 309 1.0 159 0.5 2,498 8.1 1,611 5.2
Region 4: Atlanta 254 0.4 269 0.4 438 0.7 5,030 7.6 8,900 13.3
Region 5: Chicago 193 0.4 259 0.5 855 1.6 3,074 5.9 3,562 6.8
Region 6: Dallas 179 0.4 179 0.4 157 0.4 407 1.0 1,166 2.7
Region 7: Kansas City 38 0.3 58 0.4 46 0.3 273 1.9 393 2.8
Region 8: Denver 45 0.4 40 0.3 246 2.1 172 1.4 392 3.2
Region 9: San Francisco 250 0.5 560 1.1 1,033 2.0 311 0.6 943 1.8
Region 10: Seattle 67 0.5 55 0.4 52 0.4 64 0.5 285 2.0
Source: CDC, National Notifiable Diseases Surveillance System.
* Rates per 100,000 population.
† For the case definition, see https://ndc.services.cdc.gov/conditions/hepatitis-a-acute/.
§ Numbers reported in each category might not add up to the total number of reported cases in a year because of cases with missing data or, in the case of race/ethnicity, cases categorized as “Other.”
¶ Urbanicity was categorized according to the 2013 National Center for Health Statistics (NCHS) urban-rural classification scheme for counties and county-equivalent entities (https://www.cdc.gov/nchs/data_access/urban_rural.htm). Large central metropolitan, large fringe metropolitan, medium metropolitan, and small metropolitan counties were grouped as urban. Micropolitan and noncore counties were grouped as rural.
# US Department of Health and Human Services (HHS) regions were categorized according to the grouping of states and US territories assigned under each of the 10 HHS regional offices (https://www.hhs.gov/about/agencies/iea/regional-offices/index.html). For the purposes of this report, regions with US territories (Regions 2 and 9) contain data from states only.

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This table summarizes the epidemiology of hepatitis A in the United States during recent years, highlighting the populations most affected by outbreaks of hepatitis A occurring among persons who use drugs and persons experiencing homelessness. During 2019, rates of reported hepatitis A were highest among persons aged 20–49 years, males, non-Hispanic White persons, and in the US Department of Health and Human Services Region 4 (Alabama, Florida, Georgia, Kentucky, Mississippi, North Carolina, South Carolina, and Tennessee). Using urbanicity categories defined by the National Center of Health Statistics, compared with the preoutbreak period of 2015, the rates of hepatitis A in 2019 increased 13 times in urban settings and 18 times in rural settings. Among all hepatitis A cases reported during 2019, 75% occurred among persons aged 20–49 years; 73% occurred among non-Hispanic White persons; 78% occurred in urban areas; and 47% occurred in Health and Human Services Region 4.

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