Table 3.8. Number and rates* of deaths with hepatitis C virus infection listed as a cause of death† among residents, by demographic characteristics — United States, 2015–2019

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Table 3.8. Number and rates* of deaths with hepatitis C virus infection listed as a cause of death† among residents, by demographic characteristics — United States, 2015–2019
Table 3.8.
Characteristics 2015 No. 2015 Rate*
(95% CI)		 2016 No. 2016 Rate*
(95% CI)		 2017 No. 2017 Rate*
(95% CI)		 2018 No. 2018 Rate*
(95% CI)		 2019 No. 2019 Rate*
(95% CI)
Total 19,566 4.91
(4.84-4.98)		 18,093 4.42
(4.36-4.49)		 17,253 4.13
(4.07-4.20)		 15,713 3.72
(3.66-3.78)		 14,242 3.33
(3.28-3.39)
Age (yrs)
0-34 196 0.13
(0.11-0.15)		 164 0.11
(0.09-0.13)		 180 0.12
(0.10-0.14)		 212 0.14
(0.12-0.16)		 170 0.11
(0.10-0.13)
35-44 592 1.46
(1.34-1.58)		 532 1.31
(1.20-1.43)		 507 1.24
(1.13-1.35)		 499 1.21
(1.10-1.31)		 472 1.13
(1.03-1.24)
44-54 3,659 8.47
(8.20-8.75)		 3,026 7.07
(6.82-7.32)		 2,556 6.03
(5.80-6.27)		 2,040 4.90
(4.69-5.11)		 1,676 4.10
(3.90-4.30)
55-64 9,678 23.68
(23.20-24.15)		 9,011 21.73
(21.28-22.18)		 8,275 19.70
(19.28-20.13)		 7,297 17.26
(16.87-17.66)		 6,304 14.85
(14.48-15.22)
65-74 4,009 14.55
(14.10-15.00)		 4,071 14.22
(13.78-14.66)		 4,397 14.81
(14.38-15.25)		 4,429 14.52
(14.10-14.95)		 4,499 14.29
(13.87-14.71)
≥75 1,431 7.08
(6.71-7.45)		 1,288 6.25
(5.91-6.59)		 1,329 6.28
(5.94-6.61)		 1,235 5.63
(5.32-5.94)		 1,117 4.95
(4.66-5.24)
Sex
Male 14,043 7.27
(7.15-7.40)		 12,815 6.48
(6.36-6.59)		 12,287 6.12
(6.01-6.23)		 11,242 5.53
(5.42-5.63)		 10,229 4.96
(4.86-5.05)
Female 5,523 2.71
(2.63-2.78)		 5,278 2.54
(2.47-2.61)		 4,966 2.32
(2.26-2.39)		 4,471 2.09
(2.02-2.15)		 4,013 1.83
(1.77-1.89)
Race/ethnicity
White, non-Hispanic 12,329 4.35
(4.27-4.43)		 11,389 3.95
(3.88-4.03)		 10,781 3.70
(3.63-3.78)		 9,858 3.35
(3.28-3.42)		 9,056 3.08
(3.01-3.14)
Black, non-Hispanic 3,602 8.13
(7.86-8.40)		 3,360 7.42
(7.16-7.68)		 3,262 7.03
(6.79-7.28)		 2,978 6.31
(6.08-6.54)		 2,646 5.44
(5.23-5.65)
Hispanic 2,737 6.48
(6.23-6.74)		 2,510 5.76
(5.53-6.00)		 2,399 5.29
(5.08-5.51)		 2,190 4.64
(4.44-4.84)		 1,865 3.84
(3.66-4.02)
Asian/Pacific Islander 415 2.32
(2.09-2.55)		 384 2.03
(1.82-2.24)		 368 1.86
(1.67-2.05)		 300 1.43
(1.27-1.60)		 308 1.43
(1.27-1.59)
American Indian/Alaska Native 324 11.45
(10.18-12.73)		 285 9.80
(8.63-10.97)		 299 10.24
(9.04-11.44)		 264 9.05
(7.93-10.17)		 259 8.63
(7.55-9.72)
HHS Region: Regional Office ¶
Region 1: Boston 732 3.78
(3.50-4.07)		 616 3.1
(2.85-3.35)		 602 2.97
(2.72-3.21)		 519 2.56
(2.33-2.79)		 448 2.15
(1.94-2.36)
Region 2: New York 1,379 3.78
(3.58-3.98)		 1,167 3.12
(2.94-3.30)		 1,043 2.76
(2.59-2.93)		 924 2.48
(2.31-2.64)		 780 2.06
(1.91-2.21)
Region 3: Philadelphia 1,675 4.17
(3.96-4.37)		 1,478 3.68
(3.48-3.87)		 1,441 3.53
(3.35-3.72)		 1,253 3.04
(2.87-3.22)		 1,185 2.85
(2.68-3.02)
Region 4: Atlanta 3,703 4.53
(4.38-4.68)		 3,500 4.18
(4.03-4.32)		 3,450 4.03
(3.89-4.16)		 3,160 3.60
(3.47-3.72)		 2,996 3.36
(3.24-3.49)
Region 5: Chicago 2,182 3.24
(3.11-3.38)		 2,064 3.01
(2.88-3.15)		 1,846 2.63
(2.51-2.75)		 1,762 2.52
(2.40-2.64)		 1,611 2.27
(2.15-2.38)
Region 6: Dallas 3,280 7.08
(6.83-7.33)		 3,194 6.69
(6.45-6.92)		 3,169 6.54
(6.31-6.77)		 2,907 5.85
(5.64-6.07)		 2,562 5.06
(4.86-5.25)
Region 7: Kansas City 623 3.58
(3.29-3.87)		 593 3.31
(3.04-3.59)		 589 3.24
(2.97-3.51)		 544 3.04
(2.78-3.30)		 496 2.67
(2.43-2.92)
Region 8: Denver 634 4.67
(4.30-5.04)		 640 4.69
(4.32-5.06)		 615 4.38
(4.02-4.73)		 636 4.45
(4.09-4.80)		 600 4.10
(3.77-4.44)
Region 9: San Francisco 4,053 6.84
(6.63-7.05)		 3,668 6.08
(5.88-6.28)		 3,330 5.37
(5.19-5.56)		 2,928 4.63
(4.46-4.80)		 2,564 4.00
(3.84-4.15)
Region 10: Seattle 1,305 7.49
(7.08-7.91)		 1,173 6.56
(6.17-6.94)		 1,168 6.38
(6.01-6.76)		 1,080 5.79
(5.43-6.14)		 1,000 5.27
(4.94-5.61)
Source: CDC, National Center for Health Statistics, Multiple Cause of Death 1999–2019 on CDC WONDER Online Database. Data are from the 2015–2019 Multiple Cause of Death files and are based on information from all death certificates filed in the vital records offices of the 50 states and the District of Columbia through the Vital Statistics Cooperative Program. Deaths of nonresidents (e.g., nonresident aliens, nationals living abroad, residents of Puerto Rico, Guam, the Virgin Islands, and other US territories) and fetal deaths are excluded. Numbers are slightly lower than previously reported for 2015–2016 because of NCHS standards that restrict displayed data to US residents. Accessed at http://wonder.cdc.gov/mcd-icd10.html on January 11, 2021. CDC WONDER data set documentation and technical methods can be accessed at https://wonder.cdc.gov/wonder/help/mcd.html#.
* Rates for race/ethnicity, sex, HHS region, and the overall total are age-adjusted per 100,000 US standard population during 2000 by using the following age group distribution (in years): <1, 1–4, 5–14, 15–24, 25–34, 35–44, 45–54, 55–64, 65–74, 75–84, and ≥85. Missing data are not included. For age-adjusted death rates, the age-specific death rate is rounded to 1 decimal place before proceeding to the next step in the calculation of age-adjusted death rates for NCHS Multiple Cause of Death on CDC WONDER. This rounding step might affect the precision of rates calculated for small numbers of deaths.
† Cause of death is defined as 1 of the multiple causes of death and is based on the International Classification of Diseases, 10th Rev. (ICD-10) codes B17.1, and B18.2 (hepatitis C).
¶ US Department of Health and Human Services (HHS) regions were categorized according to the grouping of states and US territories assigned under each of the 10 HHS regional offices (https://www.hhs.gov/about/agencies/iea/regional-offices/index.html). For the purposes of this report, regions with US territories (Region 2 and Region 9) contain data from states only

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This table summarizes the characteristics of hepatitis C-associated deaths among residents in the United States. During 2019, a total of 14,242 hepatitis C-associated deaths were reported among US residents in the US Multiple Cause of Death data from the National Center for Health Statistics, resulting in an age-adjusted mortality rate of 3.33 deaths per 100,000 population. Mortality rates were highest among persons aged 55–74 years, compared with other age categories, and deaths in this age group accounted for 76% of all hepatitis C-associated deaths reported during 2019. Non-Hispanic White persons accounted for 64% of all hepatitis C-associated deaths; however, the mortality rates among American Indian/Alaska Native persons and non-Hispanic Black persons were 2.8 times and 1.8 times, respectively, the mortality rate among non-Hispanic White persons. The highest hepatitis C-associated mortality rate was reported in Health and Human Services Region 10 (Alaska, Idaho, Oregon, and Washington), compared with other regions. Region-specific mortality rates have been consistently decreasing each year since 2015 for all regions except Health and Human Services Region 8 (Colorado, Montana, North Dakota, South Dakota, Utah, and Wyoming), which has had the lowest overall decrease in hepatitis C-associated mortality rate since 2015.

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