Table 2.2. Number and rates* of reported cases^† of acute hepatitis B virus infection, by demographic characteristics — United States 2015–2019

Table 2.2. Number and rates* of reported cases† of acute hepatitis B virus infection, by demographic characteristics — United States 2015–2019

Table 2.2.
Characteristics	2015 No.	2015 Rate*	2016 No.	2016 Rate*	2017 No.	2017 Rate*	2018 No.	2018 Rate*	2019 No.	2019 Rate*
Total §	3,370	1.1	3,218	1.0	3,409	1.1	3,322	1	3,192	1.0
Age group (years)
0-19	19	0.0	18	0.0	16	0.0	27	0.0	13	0.0
20-29	348	0.8	286	0.6	271	0.6	249	0.6	218	0.5
30-39	1,094	2.6	1,000	2.4	998	2.3	868	2.0	801	1.8
40-49	961	2.4	906	2.2	1,028	2.5	1,052	2.6	1,067	2.7
50-59	615	1.4	655	1.5	700	1.6	675	1.6	675	1.6
≥60	312	0.5	342	0.5	395	0.6	450	0.6	418	0.6
Sex
Male	2,080	1.3	1,957	1.2	2,095	1.3	2,050	1.3	2,021	1.3
Female	1,280	0.8	1,252	0.8	1,301	0.8	1,260	0.8	1,169	0.7
Race/ethnicity
American Indian/Alaska Native	18	0.7	14	0.5	19	0.7	25	0.9	15	0.6
Asian/Pacific Islander	67	0.4	56	0.3	64	0.3	55	0.3	63	0.3
Black, non-Hispanic	398	1.0	386	0.9	411	1.0	405	1.0	382	0.9
White, non-Hispanic	2,150	1.1	2,059	1.0	2,197	1.1	2,084	1.0	2,045	1.0
Hispanic	175	0.3	194	0.3	196	0.3	222	0.4	215	0.4
Urbanicity ^¶
Urban	2,607	1.0	2,329	0.8	2,333	0.8	2,519	0.9	2,504	0.9
Rural	631	1.4	495	1.1	490	1.1	589	1.3	519	1.2
HHS Region: Regional Office ^#
Region 1: Boston	43	0.3	93	0.7	139	1.0	115	0.8	112	0.8
Region 2: New York	165	0.6	162	0.6	138	0.5	120	0.4	163	0.6
Region 3: Philadelphia	450	1.5	397	1.3	385	1.3	311	1.0	277	0.9
Region 4: Atlanta	1,302	2.0	1,378	2.1	1,501	2.3	1,601	2.4	1,458	2.2
Region 5: Chicago	677	1.3	557	1.1	580	1.1	611	1.2	612	1.2
Region 6: Dallas	321	0.8	286	0.7	267	0.6	214	0.5	202	0.5
Region 7: Kansas City	73	0.5	79	0.6	77	0.5	51	0.4	68	0.6
Region 8: Denver	46	0.4	38	0.3	57	0.5	63	0.5	55	0.5
Region 9: San Francisco	224	0.4	151	0.3	182	0.4	154	0.3	163	0.3
Region 10: Seattle	69	0.5	77	0.6	83	0.6	82	0.6	82	0.6

Source: CDC, National Notifiable Diseases Surveillance System.
* Rates per 100,000 population.
† Reported cases that met the classification criteria for a confirmed case. For the case definition, see https://ndc.services.cdc.gov/conditions/hepatitis-b-acute/.
§ Numbers reported in each category might not add up to the total number of reported cases in a year because of cases with missing data or, in the case of race/ethnicity, cases categorized as “Other.”
¶ Urbanicity was categorized according to the 2013 National Center for Health Statistics (NCHS) urban-rural classification scheme for counties and county-equivalent entities (https://www.cdc.gov/nchs/data_access/urban_rural.htm). Large central metropolitan, large fringe metropolitan, medium metropolitan, and small metropolitan counties were grouped as urban. Micropolitan and noncore counties were grouped as rural.
# US Department of Health and Human Services (HHS) regions were categorized according to the grouping of states and US territories assigned under each of the 10 HHS regional offices (https://www.hhs.gov/about/agencies/iea/regional-offices/index.html). For the purposes of this report, regions with US territories (Region 2 and Region 9) contain data from states only.

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This table summarizes the epidemiology of acute hepatitis B in the United States in recent years. During 2019, rates of acute hepatitis B were highest among persons aged 30–59 years, males, non-Hispanic White persons, and in US Department of Health and Human Services Region 4 (Alabama, Florida, Georgia, Kentucky, Mississippi, North Carolina, South Carolina, and Tennessee). Using urbanicity categories defined by the National Center of Health Statistics, the rates of reported acute hepatitis B remained higher in rural settings, compared with urban settings during 2015–2019. Among all acute hepatitis B cases reported during 2019, 80% occurred among persons aged 30–59 years; 64% occurred among non-Hispanic White persons; 78% occurred in urban areas; and 46% occurred in Health and Human Services Region 4.

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