Blood Safety
Blood safety encompasses activities intended to mitigate risks of blood transfusion including, in part, donor selection, laboratory testing, component collection, and monitoring transfusion recipients.
Hemovigilance (HV) constitutes one aspect of blood safety, and involves monitoring the entire spectrum of blood donation and transfusion.
The HV Module developed a set of standardized national surveillance procedures used in the monitoring of transfusion-associated adverse reactions, which are aimed at improving patient safety, minimizing morbidity and mortality of transfusion recipients, and identifying emerging complications and infections associated with recipient blood transfusions.
Protocols
2023 HV Module Protocol – February 2023 [PDF – 600 KB]
Guidelines and procedures for monitoring transfusion-related reactions and incidents among reporting facilities.
Table of Contents:
- Section 1. HV Module Surveillance Overview [PDF – 600 KB]
- Section 2. HV Module Annual Facility Survey [PDF – 600 KB]
- Section 3: HV Module Adverse Reactions [PDF – 600 KB]
- Section 4. HV Module Incidents [PDF – 600 KB]
- Section 5. HV Module Denominators [PDF – 600 KB]
Supporting Chapters
Data Collection Forms & Instructions
All Data Collection Forms are Print-only
HV Module Annual Facility Surveys
Please select the appropriate annual facility survey.
- Annual Acute Care Facility Survey – August 2024 (57.300) [PDF – 100 KB]
- Annual Facility Survey Non-Acute Care Facility – August 2024 (57.306) [PDF – 100 KB]
HV Module Monthly Reporting Plan
HV Module Monthly Reporting Denominators
HV Module Adverse Reaction Forms
Please select the appropriate adverse reaction form.
- Transfusion-associated circulatory overload (TACO) – August 2024 (57.318) [PDF – 100 KB]
- Transfusion-related acute lung injury (TRALI) – August 2024 (57.317) [PDF – 100 KB]
- Transfusion Associated Dyspnea (TAD) – August 2024 (57.315) [PDF – 120 KB]
- Allergic Transfusion Reaction – August 2024 (57.308) [PDF – 100 KB]
- Hypotensive Transfusion Reaction – August 2024 (57.312) [PDF – 120 KB]
- Febrile Non-hemolytic Transfusion Reaction (FNHTR) – August 2024 (57.311) [PDF – 100 KB]
- Acute Hemolytic Transfusion Reaction (AHTR) – August 2024 (57.307) [PDF – 100 KB]
- Delayed Hemolytic Transfusion Reaction (DHTR) – August 2024 (57.309) [PDF – 100 KB]
- Delayed Serologic Transfusion Reaction (DSTR) – August 2024 (57.310) [PDF – 100 KB]
- Transfusion Associated Graft vs. Host Disease (TAGVHD) – August 2024 (57.316) [PDF – 100 KB]
- Post Transfusion Purpura (PTP) – August 2024 (57.314) [PDF – 100 KB]
- Transfusion-transmitted Infection (TTI) – August 2024 (57.313) [PDF – 100 KB]
- Other Transfusion Reaction – August 2024 (57.320) [PDF – 100 KB]
- Unknown Transfusion Reaction – August 2024 (57.319) [PDF – 120 KB]
HV Module Incident Form
HV Module Monthly Incident Summary
- HV Discard Guidance and FAQ [PDF – 125 KB]
- Quick tips for incident reporting [PDF – 313 KB]
- Annual Facility Survey Question 17 Guidance [PDF – 326 KB]
- User Guide for module-generated designations [PDF – 229 KB]
- User Guide for reporting DSTR as Other reaction [PDF – 404 KB]
- SAMS Registration Steps [PDF – 470 KB]
- Location Mapping in NHSN [PDF – 250 KB]
- Biovigilance Component Alerts [PDF – 250 KB]
- Reporting Zero Adverse Events [PDF – 200 KB]
- Linking Incident Records to Adverse Reaction Records in the Hemovigilance Module [PDF – 384 KB]
- Customizing Forms [PDF – 250 KB]
- Create a Group [PDF – 200 KB]
- Joining a Group [PDF – 300 KB]
- Maintain a Group [PDF – 250 KB]