General Best Practices for Immunization

Purpose and topics covered in this report…

History of development of: Timing and Spacing, Contraindications and Precautions, Preventing and Managing Adverse Reactions…

Vaccine scheduling, supply and lapsed schedule, spacing of doses, simultaneous and nonsimulaneous administration, licensed combination vaccines, interchangeability of formulations, extra doses, conjugate vaccines…

General principles, standards of valid contraindications and precautions, and conditions incorrectly perceived as contraindications…

Benefit and risk communication, reporting adverse reactions, National Vaccine Injury Compensation Program…

Infection control and sterile technique, route of administration, multiple and jet injections. alleviating discomfort and pain, clinical implications of nonstandard practices…

General principles, storage temperature, response to out-of-range temperature reading...

General principles, recipients of hematopoietic cell transplants, conditions or drugs that might cause immunodeficiencies...

Concurrent administration of antimicrobial agents and vaccines, administration of live vaccines and Tuberculin Skin Tests (TSTs) and Interferon-gamma Release Assays (IGRAs), vaccination of preterm infants, breastfeeding and vaccination, vaccination during pregnancy, persons vaccinated outside the United States, vaccinating persons with increased bleeding risk...

Records of healthcare providers, personal records of patients, Immunization Information Systems (IISs)...

General principles, vaccination of children and adolescents, adult vaccination, evidence-based interventions to increase vaccination coverage, other general programmatic Issues...

Information sources from "CDC-INFO Contact Center" to "Vaccine Education Center"...

Definitions from "adverse event" to "vaccine"...

Advisory Committee on Immunization Practices membership list, October 2014, members of the General Recommendations on Immunization Work Group...