Isophorone diisocyanate

Synonyms & Trade Names

IPDI, 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl-isocyanate, Isophorone diamine diisocyanate

CAS No.

4098-71-9

RTECS No.

NQ9370000

DOT ID & Guide

2290 156

Formula

C₁₂H₁₈N₂O₂

Conversion

1 ppm = 9.09 mg/m³

IDLH

N.D.
See: IDLH INDEX

Exposure Limits

NIOSH REL

TWA 0.005 ppm (0.045 mg/m³) ST 0.02 ppm (0.180 mg/m³) [skin]

OSHA PEL

none See Appendix G

Measurement Methods

NIOSH 5525;
OSHA PV2034
See: NMAM or OSHA Methods

Physical Description

Colorless to slightly yellow liquid with a pungent odor.

Molecular Weight

222.3

Boiling Point

Freezing Point

-76°F

Solubility

Decomposes

Vapor Pressure

0.0003 mmHg

Ionization Potential

Specific Gravity

1.06

Flash Point

311°F

Upper Explosive Limit

Lower Explosive Limit

Class IIIB Combustible Liquid: Fl.P. at or above 200°F.

Incompatibilities & Reactivities

Water, alcohols, phenols, amines, mercaptans, amides, urethanes, ureas [Note: Reacts with water to form carbon dioxide.]

Exposure Routes

inhalation, skin absorption, ingestion, skin and/or eye contact

Symptoms

irritation eyes, skin, respiratory system; chest tightness, dyspnea (breathing difficulty), cough, sore throat; bronchitis, wheezing, pulmonary edema; possible resp sensitization, asthma

Target Organs

Eyes, skin, respiratory system

Personal Protection/Sanitation

(See protection codes)
Skin:Prevent skin contact
Eyes:Prevent eye contact
Wash skin:When contaminated
Remove:When wet or contaminated
Change:Daily
Provide:Quick drench

First Aid

(See procedures)
Eye:Irrigate immediately
Skin:Water flush immediately
Breathing:Respiratory support
Swallow:Medical attention immediately

Respirator Recommendations

NIOSH

Up to 0.05 ppm:
(APF = 10) Any supplied-air respirator*

Up to 0.125 ppm:
(APF = 25) Any supplied-air respirator operated in a continuous-flow mode*

Up to 0.25 ppm:
(APF = 50) Any self-contained breathing apparatus with a full facepiece
(APF = 50) Any supplied-air respirator with a full facepiece

Up to 1 ppm:
(APF = 2000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode

Emergency or planned entry into unknown concentrations or IDLH conditions:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus

Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister
Any appropriate escape-type, self-contained breathing apparatus

Important additional information about respirator selection

Isophorone diisocyanate

NIOSH REL

OSHA PEL

Follow NIOSH

NIOSH Homepage