Heartland: Symptoms, Diagnosis, and Treatment

Key points

  • Symptoms of Heartland virus disease (Heartland) can include fever, fatigue (feeling tired), decreased appetite, headache, nausea, diarrhea, and muscle or joint pain.
  • If you think you or a family member might have Heartland, talk with your healthcare provider.
  • There are no vaccines to prevent or medicines to treat Heartland.
  • Rest, fluids, and pain medications may relieve symptoms.
Woman holding her head in pain while looking at a thermometer.

Symptoms

The time from infected tick bite to feeling sick (incubation period) ranges from a few days to two weeks. Signs and symptoms of Heartland are often similar to those of other tickborne illnesses, such as ehrlichiosis or anaplasmosis.

  • Most people infected with Heartland virus experience fever, fatigue (feeling tired), decreased appetite, headache, nausea, diarrhea, and muscle or joint pain.
  • Some people also have lower than normal counts of white blood cells, which help fight infections, and lower than normal counts of platelets, which help prevent bleeding.
  • Tests to check how well the liver is working (liver function tests) can show increased levels of liver enzymes.

Diagnosis

If you think you or a family member might have Heartland, talk with your healthcare provider.

  • Healthcare providers diagnose Heartland based on:
  • Your healthcare provider can order tests to look for Heartland virus infection and other infections that cause similar symptoms.

To learn more about testing, visit our Healthcare Providers page.

Treatment

  • There are no vaccines to prevent or medicines to treat Heartland. Antibiotics do not treat viruses.
  • Rest, fluids, and over-the-counter pain medications may relieve some symptoms.
  • Some patients may need to be hospitalized for intravenous fluids and supportive care for pain, fever, or other related problems.

To learn more about treatment, visit our Healthcare Providers page.