Key points
In 2021, overall tuberculosis (TB) incidence in the United States was 2.4 TB cases per 100,000 persons (24 cases per million). The United States has not achieved the 2025 national target of ≤1.3 TB cases per 100,000.
Overview
Elimination of TB is defined as reducing TB disease incidence in the United States to less than 1 case per million persons per year. Therefore, measuring the number of new cases occurring each year remains the best overall indicator of progress toward TB elimination.
In the case of incidence, the goal for states and cities is to be at or below the national target, because lower incidence of TB is the aim. State and cities are grouped into thirds based on the number of TB cases reported in 2021.
In 2021, overall TB incidence1 in the United States was 2.4 TB cases (including U.S.-born and non-U.S.–born persons) per 100,000 persons (24 cases per million). Overall, TB incidence increased from 2020 to 2021; the nation has not yet achieved the 2025 national target of ≤1.3 TB cases per 100,000.
Overall TB Incidence in the United States
- 17 states met the 2025 national target by reported incidences at or below the national target of 1.3 cases per 100,000.
- 25 states did not meet the target but fell below the national average of 2.4 cases per 100,000 (including U.S.-born and non-U.S.-born persons).
- 9 states and 9 cities reported incidences above the national target and the national average.
The left-hand side of the graph provides the state name, the TB incidence rate per 100,000 persons and the total population in each state. This is provided for additional context.
TB Incidence Among U.S.-born Persons in the United States
- 21 states met the 2025 national target of 0.4 cases per 100,000.
- 11 states were short of the 2025 target, but reported incidences at or below the national average of 0.7 cases per 100,000.
- 17 states and 9 cities were above the national average of 0.7 cases per 100,000 U.S.-born persons.
The left-hand side of the graph provides the state name, the TB incidence rate per 100,000 U.S-born persons and the total U.S. born population in each state. This is provided for additional context.
TB Incidence Among Non–U.S.-born Persons in the United States
- 11 states and 1 city met the 2025 national target of 8.8 cases per 100,000
- 12 states and 2 cities were short of the 2025 target, but reported incidences at or below the national average of 12.6 cases per 100,000
- 25 states and 6 cities were above the national average of 12.6 cases per 100,000 non-U.S.-born persons
The left-hand side of the graph provides the state name, the TB incidence rate per 100,000 non-U.S-born persons and the total non-U.S. born population in each state. This is provided for additional context.
- Centers for Disease Control and Prevention (CDC). Reported Tuberculosis in the United States, 2021. Atlanta, GA: US Department of Health and Human Services, CDC; 2022. https://www.cdc.gov/tb/statistics/reports/2021/default.htm.
- National Tuberculosis Surveillance System as of July 8, 2022; population data from the U.S. Census Bureau's American Community Survey, 2020.