Table 2. Trends in Reported Cases and Rates of Reported Cases for Nationally Notifiable STIs, United States

About

The table below is from Sexually Transmitted Infections Surveillance, 2023.

2019-2023

Disease Sex*
Cases
Percent Change
2019 2020 2021 2022 2023 5 Year 1 Year
Total Syphilis† Total 129,827 133,960 176,739 207,269 209,253 61.2 1.0
Congenital Syphilis‡ Total 1,884 2,163 2,881 3,769 3,882 106.1 3.0
Primary and Secondary Syphilis Men 32,402 33,646 41,349 44,309 39,188 20.9 -11.6
Women 6,493 7,901 12,265 14,652 13,763 112.0 -6.1
Total 38,992 41,655 53,767 59,016 53,007 35.9 -10.2
Early Non-Primary Non-Secondary Syphilis Men 34,427 35,165 40,979 44,143 40,486 17.6 -8.3
Women 7,081 7,809 10,668 12,674 13,036 84.1 2.9
Total 41,655 43,145 51,830 56,913 53,573 28.6 -5.9
Unknown Duration or Late Syphilis Men 32,411 31,868 44,548 55,094 60,718 87.3 10.2
Women 14,598 14,959 23,474 32,347 37,996 160.3 17.5
Total 47,296 46,997 68,261 87,571 98,791 108.9 12.8
Gonorrhea Men 361,586 385,551 410,388 390,548 378,428 4.7 -3.1
Women 253,359 290,666 298,015 255,566 221,176 -12.7 -13.5
Total 616,392 677,769 710,151 648,056 601,319 -2.4 -7.2
Chlamydia Men 644,337 548,676 587,473 601,205 610,445 -5.3 1.5
Women 1,160,470 1,027,061 1,053,246 1,043,573 1,033,036 -11.0 -1.0
Total 1,808,703 1,579,885 1,644,416 1,649,716 1,648,568 -8.9 -0.1
Combined Total of Total Syphilis, Gonorrhea, and Chlamydia Total 2,554,922 2,391,614 2,531,306 2,505,041 2,459,140 -3.7 -1.8

 

Disease Sex*
Rates per 100,000 Population
Percent Change
2019 2020 2021 2022 2023 5 Year 1 Year
Total Syphilis† Total 39.6 40.4 53.3 62.2 62.5 57.8 0.5
Congenital Syphilis‡ Total 50.3 59.9 78.6 102.8 105.8 110.3 2.9
Primary and Secondary Syphilis Men 20.0 20.5 25.2 26.8 23.6 18.0 -11.9
Women 3.9 4.7 7.3 8.7 8.1 107.7 -6.9
Total 11.9 12.6 16.2 17.7 15.8 32.8 -10.7
Early Non-Primary Non-Secondary Syphilis Men 21.3 21.4 24.9 26.7 24.4 14.6 -8.6
Women 4.3 4.7 6.4 7.5 7.7 79.1 2.7
Total 12.7 13.0 15.6 17.1 16.0 26.0 -6.4
Unknown Duration or Late Syphilis Men 20.0 19.4 27.1 33.3 36.6 83.0 9.9
Women 8.8 8.9 14.0 19.3 22.5 155.7 16.6
Total 14.4 14.2 20.6 26.3 29.5 104.9 12.2
Gonorrhea Men 223.7 234.8 249.7 236.3 228.3 2.1 -3.4
Women 152.1 173.8 177.9 152.1 130.7 -14.1 -14.1
Total 187.8 204.5 214.0 194.4 179.5 -4.4 -7.7
Chlamydia Men 398.6 334.2 357.4 363.7 368.3 -7.6 1.3
Women 696.6 614.1 628.8 621.2 610.7 -12.3 -1.7
Total 551.0 476.7 495.5 495.0 492.2 -10.7 -0.6
Combined Total of Total Syphilis, Gonorrhea, and Chlamydia Total 778.4 721.6 762.7 751.6 734.3 -5.7 -2.3
* Total includes cases reported with unknown sex.

† Total includes cases of syphilis (all stages) and congenital syphilis.

‡ Sex of infant is not reported. Rates are per 100,000 live births.

NOTE: Cases and rates shown in this table include District of Columbia but exclude US territories. See Technical Notes for more information. This report includes data from years that coincide with the COVID-19 pandemic, which introduced uncertainty and difficulty in interpreting case data. See Impact of COVID-19 on STIs for more information.