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Table 32. Congenital Syphilis — Reported Cases and Rates of Reported Cases by Year of Birth, by State/Territory* and Region in Alphabetical Order, United States, 2018–2022

Table 32. Congenital Syphilis — Reported Cases and Rates of Reported Cases by Year of Birth, by State/Territory* and Region in Alphabetical Order, United States, 2018–2022
State/Territory Cases Rate per 100,000 Live Births
2018 2019 2020 2021 2022 2018 2019 2020 2021 2022
Alabama 7 15 21 37 43 12.1 25.6 36.4 63.7 74.1
Alaska 1 0 8 5 12 9.9 0.0 84.5 53.4 128.1
Arizona 63 112 121 182 219 78.0 141.1 157.3 233.6 281.1
Arkansas 25 21 23 50 69 67.5 57.4 65.2 139.0 191.9
California 329 444 481 522 616 72.3 99.4 114.5 124.1 146.5
Colorado 8 10 22 30 31 12.7 15.9 35.8 47.7 49.2
Connecticut 2 3 2 7 7 5.8 8.8 6.0 19.6 19.6
Delaware 0 2 2 1 4 0.0 18.9 19.2 9.5 38.2
District of Columbia 1 1 3 6 12 10.9 11.0 33.8 69.3 138.6
Florida 109 145 154 181 276 49.2 65.9 73.4 83.7 127.6
Georgia 40 58 81 93 101 31.7 45.9 66.1 75.0 81.4
Hawaii 4 3 12 20 27 23.6 17.9 76.0 128.0 172.9
Idaho 1 1 2 5 0 4.7 4.5 9.3 22.3 0.0
Illinois 30 32 29 50 85 20.7 22.8 21.8 37.8 64.3
Indiana 1 13 8 20 38 1.2 16.1 10.2 25.0 47.5
Iowa 3 1 1 11 8 7.9 2.7 2.8 29.9 21.7
Kansas 8 9 8 7 13 22.1 25.4 23.3 20.2 37.5
Kentucky 9 9 13 25 35 16.7 17.0 25.2 47.9 67.0
Louisiana 43 68 63 110 115 72.1 115.4 109.9 191.5 200.2
Maine 0 0 0 0 3 0.0 0.0 0.0 0.0 25.0
Maryland 29 32 31 NR 45 40.8 45.6 45.2 65.9
Massachusetts 0 9 10 9 11 0.0 13.0 15.1 13.0 15.9
Michigan 14 17 29 42 36 12.7 15.8 27.9 40.0 34.3
Minnesota 10 21 7 15 20 14.8 31.8 11.0 23.3 31.0
Mississippi 3 3 37 64 73 8.1 8.2 104.3 182.0 207.6
Missouri 18 18 31 66 82 24.6 25.0 44.7 95.0 118.1
Montana 0 1 2 9 15 0.0 9.0 18.5 80.1 133.6
Nebraska 0 0 2 6 11 0.0 0.0 8.2 24.4 44.7
Nevada 31 41 46 45 65 86.9 116.9 136.7 133.6 193.0
New Hampshire 1 2 0 0 3 8.3 16.9 0.0 0.0 23.8
New Jersey 13 15 25 48 48 12.8 15.1 25.5 47.3 47.3
New Mexico 10 28 42 44 76 43.4 122.0 191.8 205.7 355.3
New York 28 27 30 42 50 12.4 12.2 14.3 19.9 23.7
North Carolina 19 27 31 43 57 16.0 22.7 26.6 35.7 47.3
North Dakota 0 0 3 2 2 0.0 0.0 29.8 19.8 19.8
Ohio 21 19 33 51 90 15.5 14.1 25.5 39.3 69.3
Oklahoma 11 42 52 85 110 22.1 85.5 109.2 175.6 227.2
Oregon 10 18 19 27 37 23.7 43.0 47.7 66.0 90.4
Pennsylvania 9 13 15 14 39 6.6 9.7 11.5 10.6 29.4
Rhode Island 0 0 1 2 5 0.0 0.0 9.9 19.1 47.8
South Carolina 9 17 19 19 25 15.9 29.8 34.1 33.2 43.7
South Dakota 1 2 4 16 40 8.4 17.5 36.5 140.7 351.8
Tennessee 13 13 31 40 61 16.1 16.2 39.4 48.9 74.6
Texas 372 530 565 684 922 98.3 140.4 153.5 183.1 246.8
Utah 1 4 1 2 7 2.1 8.5 2.2 4.3 15.0
Vermont 0 0 0 1 0 0.0 0.0 0.0 18.6 0.0
Virginia 10 11 15 18 20 10.0 11.3 15.8 18.8 20.9
Washington 6 17 10 53 52 7.0 20.0 12.0 63.2 62.0
West Virginia 1 6 9 15 13 5.5 33.1 52.0 87.2 75.6
Wisconsin 1 2 7 15 26 1.6 3.2 11.6 24.3 42.1
Wyoming 0 0 1 0 0 0.0 0.0 16.3 0.0 0.0
US TOTAL 1,325 1,882 2,162 2,875 3,755 34.9 50.2 59.8 78.5 102.5
    Northeast 53 69 83 123 166 8.7 11.5 14.4 20.8 28.1
    Midwest 107 134 162 301 451 13.4 17.1 21.5 39.6 59.3
    South 701 1,000 1,150 1,507 1,981 47.1 67.6 80.1 103.1 135.6
    West 464 679 767 944 1,157 51.6 76.6 90.6 110.7 135.6
American Samoa 0 0 0 0 0 0.0 0.0 0.0 0.0 0.0
Commonwealth of the Northern Mariana Islands 0 0 0 0 0 0.0 0.0 0.0 0.0 0.0
Guam 0 0 0 1 0 0.0 0.0 0.0 38.1 0.0
Puerto Rico 9 7 5 9 5 42.0 34.4 26.4 46.6 25.9
US Virgin Islands NR 0 0 0 0 0.0 0.0 0.0 0.0
TERRITORIES TOTAL 9 7 5 10 5 34.5 26.8 20.7 41.5 20.7
TOTAL 1,334 1,889 2,167 2,885 3,760 34.9 50.1 59.6 78.2 101.9
* Mother’s state/territory of residence was used to assign case.
NOTE: See Technical Notes for more information on syphilis case reporting and on interpreting case counts and rates in US territories. This report includes data from years that coincide with the COVID-19 pandemic, which introduced uncertainty and difficulty in interpreting case data. See Impact of COVID-19 on STIs for more information. Due to a network security incident in December 2021, the Maryland Department of Health could not finalize their 2021 STI case notification data. Although 2021 data from Maryland are included in national and regional case counts and rates displayed in this table, state-specific data have been suppressed.
NR = No report.
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