Companion Guide: NSSP ED Data on Respiratory Illness

Purpose

This companion guide offers an in-depth look at how respiratory illness cases can be extracted from syndromic surveillance data. Diagnostic codes and clinical terms used to create definitions for diagnosed COVID-19, influenza and RSV are outlined below.

Introduction

The National Syndromic Surveillance Program (NSSP) is a collaboration among CDC, local and state health departments, with private sector partners. Together, these partners collect, share, and analyze automated electronic healthcare data in near-real time.

The national data include emergency departments in all 50 states, the District of Columbia, and Guam. View the coverage map here.

Inclusion

Diagnostic codes and clinical terms were used to create definitions for diagnosed COVID-19, influenza, and RSV. Jurisdiction-level data are not shown for Missouri because the proportion of records with a discharge diagnosis is low. Jurisdiction-level data are not shown for New Hampshire, South Dakota, and Washington to ensure data use and other sharing agreements are appropriately addressed prior to public release. Guam is not shown due to small counts.

Emergency department visits were assigned to the Morbidity and Mortality Weekly Report (MMWR) week they occurred; MMWR weeks begin on Sunday and end on the following Saturday. MMWR week #1 of an MMWR year is the first week of the year that has at least four days in the calendar year.

Considerations for interpretation of data

Variability in testing practices for different viruses and in different age groups may lead to under-ascertainment of respiratory infections in electronic healthcare data, including emergency department visits. Patients who are less likely to be tested are less likely to be included. These data are based on electronic diagnostic codes transmitted automatically in near real-time, and hospital practices for assigning these codes can vary. These data are dynamic and update as codes are added and changed.

The weekly percent of emergency department visits with COVID-19 diagnosis on this site are not designed to match the percentages shown on the CDC COVID Data Tracker. Metrics will differ across websites due to factors such as updates on different days of the week or different calculations, such as presentation of a 7-day moving average on daily data rather than weekly totals. Data will also differ from state websites due to different update schedules, calculations, or definitions. These data are not a random sample and are not intended to capture data from every hospital. While these data are not designed to be randomly sampled or comprehensive, they provide a useful overall indicator of trends in emergency department use.

How percent of visits is calculated

For data that are presented as a percentage, each respiratory illness is presented as a percent of all emergency department visits by age group. For example, the COVID-19 data show emergency department visits for children ages 5-11 with diagnosed COVID-19 as a fraction of all emergency department visits for children ages 5-11.

Definitions

The following discharge diagnoses (DD) and clinical terms are included: International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM), the International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM), and Systematized Nomenclature of Medicine – Clinical Terms (SNOMED CT). Please note that conditions can be defined in different ways in electronic healthcare data, and some jurisdictions may use different definitions. Short codes listed capture all codes underneath (J09 captures J09.X1-J09.X9).

COVID-19

Definition name in the NSSP Electronic Surveillance System for the Early Notification of Community-Based Epidemics (ESSENCE) system: CDC COVID-Specific DD v1

Code Type Codes Code Description
Inclusions
ICD-10-CM J12.82 Pneumonia due to coronavirus disease 2019
U07.1 COVID-19
SNOMED CT 840539006 Disease caused by severe acute respiratory syndrome coronavirus 2
840544004 Suspected disease caused by severe acute respiratory coronavirus 2
840533007 Severe acute respiratory syndrome coronavirus 2

Influenza

Definition name in the NSSP ESSENCE system: CDC Influenza DD v1

Code Type Codes Code Description
Inclusions
ICD-10-CM J09 Influenza due to certain identified influenza viruses
J10 Influenza due to other identified influenza viruses
J11 Influenza due to unidentified influenza virus
ICD-9-CM 487.0 Influenza with pneumonia
487.1 Influenza with other respiratory manifestations
487.8 Influenza with other manifestations
488.01 Influenza due to identified avian influenza virus with pneumonia
488.09 Influenza due to identified avian influenza virus with other manifestations
488.11 Influenza due to identified 2009 H1N1 influenza virus with pneumonia
488.19 Influenza due to identified 2009 H1N1 influenza virus with other manifestations
488.81 Influenza due to identified novel influenza A virus with pneumonia
488.89 Influenza due to identified novel influenza A virus with other manifestations
SNOMED CT 442696006 Influenza caused by influenza A virus subtype H1N1
442438000 Influenza caused by Influenza A virus
6142004 Influenza
195878008 Pneumonia and influenza

RSV

Definition name in the NSSP ESSENCE system: CDC Respiratory Syncytial Virus DD v1

Code Type Codes Code Description
Inclusions
ICD-10-CM B97.4 Respiratory syncytial virus (RSV) as the cause of diseases classified elsewhere
J12.1 Respiratory syncytial virus pneumonia
J20.5 Acute bronchitis due to respiratory syncytial virus
J21.0 Acute bronchiolitis due to respiratory syncytial virus
ICD-9-CM 466.11 Acute bronchiolitis due to respiratory syncytial virus
480.1 Pneumonia due to respiratory syncytial virus
079.6 Respiratory syncytial virus
SNOMED CT 55735004 Respiratory syncytial virus infection
408684006 Healthcare associated respiratory syncytial virus disease
195881003 Pneumonia caused by respiratory syncytial virus
10625551000119103 Bronchopneumonia caused by respiratory syncytial virus
57089007 Respiratory syncytial virus bronchiolitis
195739001 Acute bronchiolitis caused by respiratory syncytial virus
79479005 Respiratory syncytial virus bronchitis
195727009 Acute respiratory syncytial virus bronchitis
72204002 Respiratory syncytial virus laryngotracheobronchitis
31309002 Respiratory syncytial virus pharyngitis