At a glance
NIOSH created a peer review plan for a draft recommended exposure limit for toluene diisocyanate. This chemical is part of a family of compounds called isocyanates that are widely used in the manufacture of flexible and rigid foams, fibers, coatings such as paints and varnishes, and elastomers. They are increasingly used in the automobile industry, autobody repair, and building insulation materials. Workers exposed to isocyanates may develop serious or fatal respiratory disease.
Overview
Title: Draft NIOSH Criteria for a Recommended Standard: Occupational Exposure to Toluene diisocyanate
Subject: A comprehensive summary of the health risks from exposure to toluene diisocyanate, exposure control guidance and a recommended exposure limit.
Purpose: The purpose of this dissemination is to present an evaluation and analysis of the scientific literature concerning potential health effects, toxicology, engineering controls, work practices, personal protective equipment and recommendations for preventing workplace exposure to toluene diisocyanates.
Timing of Review: 01/14/2022 – 03/18/2022
Primary Disciplines or Expertise Needed for Review: Toxicology, risk assessment, industrial hygiene, exposure assessment, occupational safety and health.
Type of Review: Individual letter
Number of Reviewers: 4 – 10
Reviewers Selected by: CDC/NIOSH
Public Nominations Requested for Reviewers: No
Opportunities for the Public to Comment: Yes
Peer Reviewers Provided with Public Comments Before Their Review: Yes
Have OMB requirements been deferred or waived for this dissemination? No
Will alternative peer review procedures be applied to this dissemination? No
Peer Reviewers: To be determined
Charge to Peer Reviewers: To be developed