NIOSH logo and tagline

Warfarin

Related Pages
Synonyms & Trade Names
3-(α-Acetonyl)-benzyl-4-hydroxycoumarin, 4-Hydroxy-3-(3-oxo-1-phenyl butyl)-2H-1-benzopyran-2-one, WARF
CAS No.
81-81-2
RTECS No.
GN4550000
DOT ID & Guide
Formula
C₁₉H₁₆O₄
Conversion
IDLH
100 mg/m3
See: 81812
Exposure Limits
NIOSH REL
TWA 0.1 mg/m3
OSHA PEL
TWA 0.1 mg/m3
Measurement Methods
NIOSH 5002
See: NMAM or OSHA Methods
Physical Description
Colorless, odorless, crystalline powder. [Note: Rodenticide.]
Molecular Weight
308.3
Boiling Point
Decomposes
Melting Point
322°F
Solubility
0.002%
Vapor Pressure
(71°F): 0.09 mmHg
Ionization Potential
?
Specific Gravity
?
Flash Point
?
Upper Explosive Limit
?
Lower Explosive Limit
?
Combustible Solid
Incompatibilities & Reactivities
Strong oxidizers
Exposure Routes
inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms
hematuria (blood in the urine), back pain; hematoma arms, legs; epistaxis (nosebleed), bleeding lips, mucous membrane hemorrhage; abdominal pain, vomiting, fecal blood; petechial rash; abnormal hematologic indices
Target Organs
Blood, cardiovascular system
Personal Protection/Sanitation
(See protection codes)
Skin:Prevent skin contact
Eyes:No recommendation
Wash skin:When contaminated
Remove:When wet or contaminated
Change:Daily
First Aid
(See procedures)
Eye:Irrigate immediately
Skin:Soap wash promptly
Breathing:Respiratory support
Swallow:Medical attention immediately
Respirator Recommendations

NIOSH/OSHA

Up to 0.5 mg/m3:
(APF = 5) Any quarter-mask respirator.
Click here for information on selection of N, R, or P filters.

Up to 1 mg/m3:
(APF = 10) Any particulate respirator equipped with an N95, R95, or P95 filter (including N95, R95, and P95 filtering facepieces) except quarter-mask respirators. The following filters may also be used: N99, R99, P99, N100, R100, P100.
Click here for information on selection of N, R, or P filters.
(APF = 10) Any supplied-air respirator

Up to 2.5 mg/m3:
(APF = 25) Any supplied-air respirator operated in a continuous-flow mode
(APF = 25) Any powered, air-purifying respirator with a high-efficiency particulate filter.

Up to 5 mg/m3:


(APF = 50) Any air-purifying, full-facepiece respirator with an N100, R100, or P100 filter.
Click here for information on selection of N, R, or P filters. 


(APF = 50) Any supplied-air respirator that has a tight-fitting facepiece and is operated in a continuous-flow mode
(APF = 50) Any powered, air-purifying respirator with a tight-fitting facepiece and a high-efficiency particulate filter
(APF = 50) Any self-contained breathing apparatus with a full facepiece
(APF = 50) Any supplied-air respirator with a full facepiece

Up to 100 mg/m3:
(APF = 1000) Any supplied-air respirator operated in a pressure-demand or other positive-pressure mode

Emergency or planned entry into unknown concentrations or IDLH conditions:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus

Escape:


(APF = 50) Any air-purifying, full-facepiece respirator with an N100, R100, or P100 filter.
Click here for information on selection of N, R, or P filters. 


Any appropriate escape-type, self-contained breathing apparatus

Important additional information about respirator selection

See also
INTRODUCTION   ICSC CARD: 0821   MEDICAL TESTS: 0242
Page last reviewed: October 30, 2019
Content source: National Institute for Occupational Safety and Health