NIOSH logo and tagline

Isopropyl acetate

Related Pages
Synonyms & Trade Names
Isopropyl ester of acetic acid, 1-Methylethyl ester of acetic acid, 2-Propyl acetate
CAS No.
108-21-4
RTECS No.
AI4930000
DOT ID & Guide
1220 129
Formula
CH₃COOCH(CH₃)₂
Conversion
1 ppm = 4.18 mg/m3
IDLH
1800 ppm
See: 108214
Exposure Limits
NIOSH REL
See Appendix D
OSHA PEL
TWA 250 ppm (950 mg/m3) See Appendix G
Measurement Methods
NIOSH 1454 , 1460;
OSHA 7
See: NMAM or OSHA Methods
Physical Description
Colorless liquid with a fruity odor.
Molecular Weight
102.2
Boiling Point
194°F
Freezing Point
-92°F
Solubility
3%
Vapor Pressure
42 mmHg
Ionization Potential
9.95 eV
Specific Gravity
0.87
Flash Point
36°F
Upper Explosive Limit
8%
Lower Explosive Limit
(100°F): 1.8%
Class IB Flammable Liquid: Fl.P. below 73°F and BP at or above 100°F.
Incompatibilities & Reactivities
Nitrates; strong oxidizers, alkalis & acids
Exposure Routes
inhalation, ingestion, skin and/or eye contact
Symptoms
irritation eyes, skin, nose; dermatitis; In Animals: narcosis
Target Organs
Eyes, skin, respiratory system, central nervous system
Personal Protection/Sanitation
(See protection codes)
Skin:Prevent skin contact
Eyes:Prevent eye contact
Wash skin:When contaminated
Remove:When wet (flammable)
Change:No recommendation
First Aid
(See procedures)
Eye:Irrigate immediately
Skin:Water flush promptly
Breathing:Respiratory support
Swallow:Medical attention immediately
Respirator Recommendations

OSHA

Up to 1800 ppm:
(APF = 25) Any supplied-air respirator operated in a continuous-flow mode£
(APF = 50) Any self-contained breathing apparatus with a full facepiece
(APF = 50) Any supplied-air respirator with a full facepiece

Emergency or planned entry into unknown concentrations or IDLH conditions:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus

Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister
Any appropriate escape-type, self-contained breathing apparatus

Important additional information about respirator selection

See also
INTRODUCTION   ICSC CARD: 0907
Page last reviewed: October 30, 2019
Content source: National Institute for Occupational Safety and Health