The National Institute for Occupational Safety and Health (NIOSH)

Tungsten carbide, mixed with cobalt (85%:15%)

RTECS #

YO7350000

CAS #

11107-01-0
See: NMAM or OSHA Methods

Updated

December 2016

Molecular Weight

N/R

Molecular Formula

N/R

Synonyms

BK15

Acute Toxicity Data and References

Route/Organism	Dose	Effect	Reference
In Vitro/Human, lung	Inhibitor Concentration Low: 1 mg/mL/48H	In Vitro Toxicity Studies: Cell viability (mitochondrial reductase assays): MTT, XTT, MTS, WSTs assays etc.	TXAPA9 278,1,2014
In Vitro/Human, lung	Inhibitor Concentration Low: 100 mg/mL/1H	In Vitro Toxicity Studies: Cell viability (mitochondrial reductase assays): MTT, XTT, MTS, WSTs assays etc.	TXAPA9 278,1,2014
In Vitro/Human, lung	Inhibitor Concentration Low: 1000 mg/mL/12H	In Vitro Toxicity Studies: Apoptosis in vitro	TXAPA9 278,1,2014
intratracheal/rat	lowest published lethal dose: 50 mg/kg		NTIS** AEC-TR-6710

Reviews

Organization	Standard	Reference
American Conference of Governmental Industrial Hygienists (ACGIH)	Threshold Limit Value-time-weighted average 0.02 mg(Co)/m3	DTLVS* TLV/BEI,2013
American Conference of Governmental Industrial Hygienists (ACGIH)	Threshold Limit Value-time-weighted average 5 mg(week)/m3;short term exposure limit 10 mg(week)/m3	DTLVS* TLV/BEI,2013
American Conference of Governmental Industrial Hygienists (ACGIH)	Threshold Limit Value-Confirmed animal carcinogen	DTLVS* TLV/BEI,2013
TOXICOLOGY REVIEW		MUTAEX 15,431,2000

Standards and Regulations

Organization	Standard	Reference
Occupational Exposure Limit-BELGIUM	time-weighted average 5 mg(W)/m³, short term exposure limit 10 mg(W)/m³, MAR2002
Occupational Exposure Limit-HUNGARY	time-weighted average 0.1 mg(Co)/m³, short term exposure limit 0.4 mg(Co)/m³, SEP2000
Occupational Exposure Limit-NEW ZEALAND	time-weighted average 1 mg(W)/m³, JAN2002
Occupational Exposure Limit-SWITZERLAND	MAK-week 5 mg(W)/m³, inhal, JAN2011
Occupational Exposure Limit-UNITED KINGDOM	time-weighted average 0.1 mg(Co)/m³, sen, OCT2007
Occupational Exposure Limit-UNITED KINGDOM	time-weighted average 5 mg(W)/m³;short term exposure limit 10 mg(W)/m³, OCT2007

NIOSH Documentation and Surveillance

Organization	Standard	Reference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO CEMENTED TUNGSTEN CARBIDE-air	10H time-weighted average 0.1 mg(Co)/m³	NIOSH* DHHS #92-100,1992

Page last reviewed: November 16, 2018

Content source: National Institute for Occupational Safety and Health

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