Toluenediamine
RTECS #
XS9445000
CAS #
Updated
July 2010
Molecular Weight
122.19
Molecular Formula
C7H10N2
Synonyms
Benzenediamine, ar-methyl-
Diaminotoluene
Methylphenylenediamine
RCRA waste number U221
TDA 8020
Tolylenediamine
Diaminotoluene
Methylphenylenediamine
RCRA waste number U221
TDA 8020
Tolylenediamine
Acute Toxicity Data and References
Route/Organism | Dose | Effect | Reference |
---|---|---|---|
intraperitoneal/mouse | lethal dose (50 percent kill): 240 mg/kg | ZHYGAM 29,395,1983 | |
intraperitoneal/rat | lethal dose (50 percent kill): 230 mg/kg | ZHYGAM 29,395,1983 | |
intravenous/mouse | lethal dose (50 percent kill): 90 mg/kg | ZHYGAM 29,395,1983 | |
intravenous/rat | lethal dose (50 percent kill): 350 mg/kg | ZHYGAM 29,395,1983 | |
oral/mouse | lethal dose (50 percent kill): 350 mg/kg | ZHYGAM 29,395,1983 | |
oral/rat | lethal dose (50 percent kill): 270 mg/kg | ZHYGAM 29,395,1983 | |
skin/rat | lethal dose (50 percent kill): 463 mg/kg | Peripheral Nerve and Sensation: Spastic paralysis with/without sensory change Lung, Thorax, or Respiration: Cyanosis Kidney, Ureter, and Bladder: Other changes in urine composition | NTIS** OTS0544321 |
Reviews
Organization | Standard | Reference |
---|---|---|
TOXICOLOGY REVIEW | REPTED 29,10,2010 |
Standards and Regulations
Organization | Standard | Reference |
---|---|---|
Occupational Exposure Limit-RUSSIA | short term exposure limit 2 mg/m3, Skin, JUN2003 |
NIOSH Documentation and Surveillance
Status in Federal Agencies
Organization | Reference |
---|---|
EPA TSCA 8(a) PRELIMINARY ASSESSMENT INFORMATION, PROPOSED RULE | FEREAC 47,27009,82 |
EPA TSCA Section 8(b) CHEMICAL INVENTORY | |
EPA TSCA Section 8(d) unpublished health/safety studies | |
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001 |
Page last reviewed: November 16, 2018
Content
source: National Institute for Occupational Safety and Health