Talc (powder), containing no asbestos fibers

RTECS #

WW2710000

CAS #

14807-96-6; 11119-41-8; 12420-12-1; 37232-12-5; 99638-63-8; 110540-41-5
See: NMAM or OSHA Methods

Updated

March 2016

Molecular Weight

96.33

Molecular Formula

H₂₀₃Si·3/₄Mg

Synonyms

Agalite
Asbestine
B 13
B 13 (mineral)
B 13(mineral)
B 9
B 9 (talc)
Beaver White 200
Beaver White 325
Cimflex 606
Circron MP
CP 10-40
CP 38-33
Crown Talc W 83
Crown Talc Z
Crystalite CRS 6002
CT 8 (mineral)
Cubic Master
Desertalc 57
Emtal 500
Emtal 549
Emtal 596
Emtal 599
EX-IT
Fibrene C 400
Finntalc C10
Finntalc M05
Finntalc M15
Finntalc P40
Finntalc PF
FW-XO
IT Extra
LMR 100
Micro Ace K1
Micro Ace L1
Micron White 5000A
Micron White 5000P
Micron White 5000S
Microtalco IT Extra
Mistron 139
Mistron 2SC
Mistron frost P
Mistron RCS
Mistron Star
Mistron super frost
Mistron vapor
MP 12-50
MP 25-38
MP 40-27
MP 45-26
MST
Mussolinite
Nytal 200
Nytal 400
P 3
P 3 (Mineral)
PK-C
PK-N
Polytal 4641
Polytal 4725
Silicate: talc, containing no asbestos (OSHA)
Steawhite
Supreme
Supreme dense
Talc
Talc (ACGIH)
Talc, containing no asbestos fibers
Talcan PK-P
Talcron CP 44-31
Talcum
TY 80

Skin and Eye Irritation and References

Route/Organism	Dose	Effect	Reference
skin /human	300 µg/3D- intermittent	mild	85DKA8 -,127,1977

Tumorigenic Data and References

Route/Organism	Dose	Effect	Reference
inhalation/rat	lowest published toxic concentration: 18 mg/m³/6H/2Y- intermittent	Tumorigenic: Carcinogenic by RTECS criteria Lung, Thorax, or Respiration: Bronchogenic carcinoma Endocrine: Tumors	NTPTR* NTP-TR-421,1993
inhalation/rat	toxic concentration: 11 mg/m³/1Y- intermittent	Tumorigenic: Equivocal tumorigenic agent by RTECS criteria Lung, Thorax, or Respiration: Tumors	43GRAK -,389,1979

Other Multiple Dose Data and References

Route/Organism	Dose	Effect	Reference
inhalation/mouse	lowest published toxic concentration: 20400 µg/m³/6H/26D- intermittent	Lung, Thorax, or Respiration: Other changes	ENVRAL 49,233,1989
inhalation/rat	lowest published toxic concentration: 17 mg/m³/6H/26D- intermittent	Lung, Thorax, or Respiration: Other changes	ENVRAL 49,233,1989

Reviews

Organization	Standard	Reference
American Conference of Governmental Industrial Hygienists (ACGIH)	Threshold Limit Value-time-weighted average 2 mg/m³ (resp particulate)	DTLVS* TLV/BEI,2013
American Conference of Governmental Industrial Hygienists (ACGIH)	Threshold Limit Value-Not classifiable as a human carcinogen	DTLVS* TLV/BEI,2013
International Agency for Research on Cancer (IARC)	Cancer Review:Animal Limited Evidence (perin	IMEMDT 93,412,2010
International Agency for Research on Cancer (IARC)	Cancer Review:Animal Inadequate Evidence	IMEMDT 42,185,1987
International Agency for Research on Cancer (IARC)	Cancer Review:Human Inadequate Evidence	IMEMDT 42,185,1987
International Agency for Research on Cancer (IARC)	Cancer Review:Human Limited Evidence (perine	IMEMDT 93,412,2010
International Agency for Research on Cancer (IARC)	Cancer Review:Human Inadequate Evidence (inh	IMEMDT 93,412,2010
International Agency for Research on Cancer (IARC)	Cancer Review:Group 3	IMSUDL 7,349,1987
International Agency for Research on Cancer (IARC)	Cancer Review:Group 3 (inhaled)	IMEMDT 93,412,2010
International Agency for Research on Cancer (IARC)	Cancer Review:Group 2B (perineal use)	IMEMDT 93,412,2010
TOXICOLOGY REVIEW		EMMUEG 39,69,2002
TOXICOLOGY REVIEW		DIMON* 40,258,1994
TOXICOLOGY REVIEW		ENTOX* -,131,2005

Standards and Regulations

Organization	Standard	Reference
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIA	time-weighted average 2.5 mg/m³, JUL2008
Occupational Exposure Limit-AUSTRIA	MAK-TMW 2 mg/m³, resp, 2007
Occupational Exposure Limit-BELGIUM	time-weighted average 2 mg/m³, MAR2002
Occupational Exposure Limit-DENMARK	time-weighted average 0.3 f/cc, carc, MAY2011
Occupational Exposure Limit-FINLAND	time-weighted average 0.5 mg/m³, NOV2011
Occupational Exposure Limit-ICELAND	time-weighted average 0.3 f/cc, NOV2011
Occupational Exposure Limit-JAPAN	Occupational Exposure Limit 0.5 mg/m³ (resp. dust), 2 mg/m³ (total dust), MAY2012
Occupational Exposure Limit-KOREA	time-weighted average 2 mg/m³, 2006
Occupational Exposure Limit-MEXICO	time-weighted average 2 mg/m³ (respirable), 2004
Occupational Exposure Limit-NEW ZEALAND	time-weighted average 2 mg/m³ (respirable dust), JAN2002
Occupational Exposure Limit-PERU	time-weighted average 2 mg/m³, JUL2005
Occupational Exposure Limit-SWEDEN	time-weighted average 2 mg/cm³ (total dust);time-weighted average 1 mg/cm³ (resp. dust), JUN2005
Occupational Exposure Limit-SWITZERLAND	MAK-week 2 mg/m³, resp, JAN2011
Occupational Exposure Limit-THE NETHERLANDS	MAC-TGG 1 mg/m³, 2003
Occupational Exposure Limit-UNITED KINGDOM	time-weighted average 1 mg/m³ (resp. dust), OCT2007
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)	8H time-weighted average 20 mppcf, respirable dust	CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)	8H time-weighted average 20 mppcf, respirable dust	CFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)	8H time-weighted average 20 mppcf, respirable dust	CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)	8H time-weighted average 20 mppcf	CFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

Organization	Standard	Reference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO TALC (containing no asbestos)-air	10H 2 mg/m³	NIOSH* PHS #92-100,1992
National Occupational Exposure Survey 1983	Hazard Code X9093; Number of Industries 2; Total Number of Facilities 273; Number of Occupations 2; Total Number of Employees Exposed 4245; Total Number of Female Employees Exposed 590
National Occupational Exposure Survey 1983	Hazard Code 71055; Number of Industries 313; Total Number of Facilities 82650; Number of Occupations 192; Total Number of Employees Exposed 1367384; Total Number of Female Employees Exposed 348973
National Occupational Hazard Survey 1974	Hazard Code 71055; Number of Industries 243; Total Number of Facilities 38349; Number of Occupations 149; Total Number of Employees Exposed 527353

Status in Federal Agencies

Organization	Reference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NCI Carcinogenesis Studies (inhal);clear evidence:rat
NCI Carcinogenesis Studies (inhal);no evidence:mouse

Page last reviewed: November 16, 2018

Content source: National Institute for Occupational Safety and Health