Selenium
RTECS #
VS7700000
CAS #
Updated
June 2017
Molecular Weight
78.96
Molecular Formula
Se
Synonyms
C.I. 77805
Colloidal selenium
Elemental selenium
Selen (Polish)
Selenate
Selenium (ACGIH)
Selenium alloy
Selenium base
Selenium dust
Selenium elemental
Selenium homopolymer
Vandex
Colloidal selenium
Elemental selenium
Selen (Polish)
Selenate
Selenium (ACGIH)
Selenium alloy
Selenium base
Selenium dust
Selenium elemental
Selenium homopolymer
Vandex
Reproductive Effects Data and References
Route/Organism | Dose | Effect | Reference |
---|---|---|---|
oral/mouse | 134 mg/kg (multigenerations) | Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus) Reproductive: Effects on embryo or fetus: Fetal death | AEHLAU 23,102,1971 |
oral/rat | 1.925 mg/kg (56D prior to copulation/1-21D pregnant) | Reproductive: Effects on newborn: Other neonatal measures or effects | FCTOD7 48,3486,2010 |
Tumorigenic Data and References
Route/Organism | Dose | Effect | Reference |
---|---|---|---|
oral/mouse | lowest published toxic dose: 480 mg/kg/60D- continuous | Tumorigenic: Equivocal tumorigenic agent by RTECS criteria Skin and Appendages: Tumors | YMBUA7 11,368,1960 |
Acute Toxicity Data and References
Route/Organism | Dose | Effect | Reference |
---|---|---|---|
inhalation/rat | Lowest published lethal concentration: 33 mg/m3/8H | Blood: Hemorrhage Lung, Thorax, or Respiration: Acute pulmonary edema Lung, Thorax, or Respiration: Changes in lung weight | AMIHBC 4,458,1951 |
inhalation/rat | Lowest published lethal concentration: 30 mg/m3 | Lung, Thorax, or Respiration: Other changes Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation | HBTME* -,783,2007 |
intravenous/rabbit | lowest published lethal dose: 2500 µg/kg | JOBSAK 35,693,1928 | |
intravenous/rat | lethal dose (50 percent kill): 6 mg/kg | AMIHBC 4,458,1951 | |
oral/rat | lethal dose (50 percent kill): 6700 mg/kg | Behavioral: Somnolence (general depressed activity) Lung, Thorax, or Respiration: Dyspnea Nutritional and Gross Metabolic: Other changes | TXAPA9 20,89,1971 |
parenteral/cattle | lowest published lethal dose: 0.5 mg/kg | Lung, Thorax, or Respiration: Acute pulmonary edema Lung, Thorax, or Respiration: Dyspnea Gastrointestinal: Changes in structure or function of salivary glands | VCVN5* -,268,1993 |
Other Multiple Dose Data and References
Route/Organism | Dose | Effect | Reference |
---|---|---|---|
oral/human | lowest published toxic dose: 23.7 mg/kg/13W- continuous | Behavioral: Somnolence (general depressed activity) Skin and Appendages: Other: Hair Skin and Appendages: Other: Nails | VCVN5* -,273,1989 |
oral/human | lowest published toxic dose: 2.38 mg/kg/7D- intermittent | Gastrointestinal: Hypermotility, diarrhea Skin and Appendages: Other: Hair Skin and Appendages: Other: Nails | CTOXAO 47,745,2009 |
oral/rat | lowest published toxic dose: 3 mg/kg/30D- intermittent | Liver: Other changes Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol) Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Transaminases | PHREP* 60,199,2008 |
Reviews
Organization | Standard | Reference |
---|---|---|
American Conference of Governmental Industrial Hygienists (ACGIH) | Threshold Limit Value-time-weighted average 0.2 mg/m3 | DTLVS* TLV/BEI,2013 |
International Agency for Research on Cancer (IARC) | Cancer Review:Human Inadequate Evidence | IMEMDT 9,245,1975 |
International Agency for Research on Cancer (IARC) | Cancer Review:Animal Inadequate Evidence | IMEMDT 9,245,1975 |
International Agency for Research on Cancer (IARC) | Cancer Review:Group 3 | IMSUDL 7,56,1987 |
TOXICOLOGY REVIEW | CTOXAO 6,459,1973 | |
TOXICOLOGY REVIEW | CTOXAO 5,175,1972 | |
TOXICOLOGY REVIEW | CRTXB2 4(3),271,1976 | |
TOXICOLOGY REVIEW | JAVMA4 164,277,1974 | |
TOXICOLOGY REVIEW | CTOXAO 5,151,1972 | |
TOXICOLOGY REVIEW | IJMDAI 10,416,1974 | |
TOXICOLOGY REVIEW | JAMAAP 116,562,1941 | |
TOXICOLOGY REVIEW | CHREAY 28,179,1941 | |
TOXICOLOGY REVIEW | ADTEAS 5,51,1972 | |
TOXICOLOGY REVIEW | PHREA7 23,305,1943 | |
TOXICOLOGY REVIEW | FOREAE 7,313,1942 | |
TOXICOLOGY REVIEW | KOTTAM 11,1300,1975 | |
TOXICOLOGY REVIEW | 85CVA2 5,63,1970 | |
TOXICOLOGY REVIEW | PEXTAR 12,102,1969 | |
TOXICOLOGY REVIEW | BNYMAM 54,413,1978 | |
TOXICOLOGY REVIEW | AMTODM 3,209,1977 | |
TOXICOLOGY REVIEW | JEPTDQ 4(1),193,1980 | |
TOXICOLOGY REVIEW | MEHYDY 5,877,1979 | |
TOXICOLOGY REVIEW | CTOXAO 17,171,1980 | |
TOXICOLOGY REVIEW | JACTDZ 5(1),45,1986 | |
TOXICOLOGY REVIEW | TOLED5 137,103,2003 | |
TOXICOLOGY REVIEW | PHTOEH 93,105,2003 | |
TOXICOLOGY REVIEW | NRTXDN 27,429,2006 | |
TOXICOLOGY REVIEW | TOXID9 227,1,2006 | |
TOXICOLOGY REVIEW | JJATDK 26,191,2006 | |
TOXICOLOGY REVIEW | ENTOX* -,774,2005 | |
TOXICOLOGY REVIEW | REPTED 23,260,2007 | |
TOXICOLOGY REVIEW | HBTME* ,783,2007 | |
TOXICOLOGY REVIEW | HTOPA* 1,595,2002 | |
TOXICOLOGY REVIEW | MUREAV 690,71,2010 | |
TOXICOLOGY REVIEW | NTAPM* -,629,1995 | |
TOXICOLOGY REVIEW | TXCYAC 278,27,2010 | |
TOXICOLOGY REVIEW | REPTED 38,1,2013 | |
TOXICOLOGY REVIEW | MUREAV 733,1,2012 | |
TOXICOLOGY REVIEW | FCTOD7 86,298,2015 | |
TOXICOLOGY REVIEW | MUREAV 770,12,2016 |
Standards and Regulations
Organization | Standard | Reference |
---|---|---|
Mine Safety and Health Administration (MSHA) STANDARD-air | time-weighted average 0.2 mg(Se)/m3 | DTLVS* 3,224,1971 |
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV; | ||
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV | ||
Occupational Exposure Limit-ARAB Republic of Egypt | time-weighted average 0.2 mg/m3, JAN1993 | |
Occupational Exposure Limit-AUSTRALIA | time-weighted average 0.1 mg/m3, JUL2008 | |
Occupational Exposure Limit-AUSTRIA | MAK-TMW 0.1 mg/m3;KZW 0.3 mg/m3, inhal, 2007 | |
Occupational Exposure Limit-BELGIUM | time-weighted average 0.2 mg/m3, MAR2002 | |
Occupational Exposure Limit-DENMARK | time-weighted average 0.1 mg(Se)/m3, MAY2011 | |
Occupational Exposure Limit-GERMANY | MAK 0.02 mg/m3, inhal, skin, 2011 | |
Occupational Exposure Limit-HUNGARY | time-weighted average 0.1 mg/m3, short term exposure limit 0.4 mg/m3, SEP2000 | |
Occupational Exposure Limit-ICELAND | time-weighted average 0.1 mg/m3, NOV2011 | |
Occupational Exposure Limit-JAPAN | Occupational Exposure Limit 0.1 mg/m3, MAY2012 | |
Occupational Exposure Limit-KOREA | time-weighted average 0.2 mg/m3, 2006 | |
Occupational Exposure Limit-MEXICO | time-weighted average 0.2 mg/m3, 2004 | |
Occupational Exposure Limit-NEW ZEALAND | time-weighted average 0.1 mg/m3, JAN2002 | |
Occupational Exposure Limit-PERU | time-weighted average 0,2 mg/m3, JUL2005 | |
Occupational Exposure Limit-POLAND | MAC(time-weighted average) 0.1 mg/m3, MAC(short term exposure limit) 0.3 mg/m3, JAN1999 | |
Occupational Exposure Limit-RUSSIA | time-weighted average 2 mg/m3, JUN2003 | |
Occupational Exposure Limit-SWEDEN | time-weighted average 0.1 mg/m3 (total dust), JUN2005 | |
Occupational Exposure Limit-SWITZERLAND | MAK-week 0.02 mg/m3, KZG-week 0.16 mg/m3, inhal, skin, JAN2011 | |
Occupational Exposure Limit-THE NETHERLANDS | MAC-TGG 0.1 mg(Se)/m3, 2003 | |
Occupational Exposure Limit-THE PHILIPPINES | time-weighted average 0.2 mg/m3, JAN1993 | |
Occupational Exposure Limit-TURKEY | time-weighted average 0.2 mg/m3, JAN1993 | |
Occupational Exposure Limit-UNITED KINGDOM | time-weighted average 0.1 mg/m3, OCT2007 | |
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) | 8H time-weighted average 0.2 mg(Se)/m3 | CFRGBR 29,1926.55,1994 |
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) | 8H time-weighted average 0.2 mg(Se)/m3 | CFRGBR 41,50-204.50,1994 |
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) | 8H time-weighted average 0.2 mg(Se)/m3 | CFRGBR 29,1910.1000,1994 |
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) | 8H time-weighted average 0.2 mg(Se)/m3 | CFRGBR 29,1915.1000,1993 |
NIOSH Documentation and Surveillance
Organization | Standard | Reference |
---|---|---|
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO SELENIUM COMPOUNDS (as Se)-air | 10H time-weighted average 0.2 mg/m3 | NIOSH* DHHS #92-100,1992 |
National Occupational Exposure Survey 1983 | Hazard Code X2074; Number of Industries 2; Total Number of Facilities 105; Number of Occupations 2; Total Number of Employees Exposed 105 | |
National Occupational Exposure Survey 1983 | Hazard Code 68295; Number of Industries 23; Total Number of Facilities 1102; Number of Occupations 68; Total Number of Employees Exposed 27208; Total Number of Female Employees Exposed 9632 | |
National Occupational Hazard Survey 1974 | Hazard Code 68295; Number of Industries 8; Total Number of Facilities 403; Number of Occupations 10; Total Number of Employees Exposed 2147 |
Status in Federal Agencies
Page last reviewed: November 16, 2018
Content
source: National Institute for Occupational Safety and Health