Pyridine, 2-chloro-6-(trichloromethyl)-
RTECS #
US7525000
CAS #
Updated
September 2013
Molecular Weight
230.90
Molecular Formula
C6H3Cl4N
Synonyms
2-Chloro-6-(trichloromethyl)pyridine
2-Chloro-6-(trichloromethyl)pyridine (ACGIH:OSHA)
Dowco-163
Nitrapyrin
Nitrapyrin (ACGIH)
N-Serve
N-Serve nitrogen stabilizer
2-Chloro-6-(trichloromethyl)pyridine (ACGIH:OSHA)
Dowco-163
Nitrapyrin
Nitrapyrin (ACGIH)
N-Serve
N-Serve nitrogen stabilizer
Mutation Data and Reference
System Test | Route/Organism/Tissue | Dose | Reference |
---|---|---|---|
mutation in microorganisms | /Salmonella typhimurium | 100 µg/plate (-enzymatic activation step) | EMMUEG 11(Suppl 12),1,1988 |
Reproductive Effects Data and References
Route/Organism | Dose | Effect | Reference |
---|---|---|---|
oral/rabbit | 390 mg/kg (6-18D pregnant) | Reproductive: Specific developmental abnormalities: Craniofacial (including nose and tongue) | FAATDF 11,464,1988 |
Acute Toxicity Data and References
Route/Organism | Dose | Effect | Reference |
---|---|---|---|
oral/chicken | lethal dose (50 percent kill): 235 mg/kg | 28ZEAL 5,166,1976 | |
oral/mouse | lethal dose (50 percent kill): 710 mg/kg | GUCHAZ 6,122,1973 | |
oral/rabbit | lethal dose (50 percent kill): 713 mg/kg | FAATDF 11,464,1988 | |
oral/rat | lethal dose (50 percent kill): 940 mg/kg | PCOC** -,819,1966 | |
skin/rabbit | lethal dose (50 percent kill): 850 mg/kg | PCOC** -,819,1966 | |
unreported route/mouse | lethal dose (50 percent kill): 3113 mg/kg | GISAAA 48(4),52,1983 | |
unreported route/rat | lethal dose (50 percent kill): 3675 mg/kg | GISAAA 48(4),52,1983 |
Reviews
Organization | Standard | Reference |
---|---|---|
American Conference of Governmental Industrial Hygienists (ACGIH) | Threshold Limit Value-time-weighted average 10 mg/m3;short term exposure limit 20 mg/m3 | DTLVS* TLV/BEI,2013 |
American Conference of Governmental Industrial Hygienists (ACGIH) | Threshold Limit Value-Not classifiable as a human carcinogen | DTLVS* TLV/BEI,2013 |
TOXICOLOGY REVIEW | DOEAAH 32,22,1976 | |
TOXICOLOGY REVIEW | FEREAC 72,53455,2007 | |
TOXICOLOGY REVIEW | RTOPDW 51,53,2008 |
Standards and Regulations
Organization | Standard | Reference |
---|---|---|
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION | FEREAC 54,7740,1989 | |
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDES | Supported | RBREV* -,137,1998 |
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV; | ||
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV | ||
Occupational Exposure Limit-AUSTRALIA | time-weighted average 10 mg/m3, short term exposure limit 20 mg/m3, JUL2008 | |
Occupational Exposure Limit-BELGIUM | time-weighted average 10 mg/m3, short term exposure limit 20 mg/m3, MAR2002 | |
Occupational Exposure Limit-FRANCE | VME 10 mg/m3, FEB2006 | |
Occupational Exposure Limit-KOREA | time-weighted average 10 mg/m3, short term exposure limit 20 mg/m3, 2006 | |
Occupational Exposure Limit-MEXICO | time-weighted average 10 mg/m3;short term exposure limit 20 mg/m3, 2004 | |
Occupational Exposure Limit-NEW ZEALAND | time-weighted average 10 mg/m3, short term exposure limit 20 ppm, JAN2002 | |
Occupational Exposure Limit-PERU | time-weighted average 10 mg/m3; short term exposure limit 20 mg/m3, JUL2005 | |
Occupational Exposure Limit-SWITZERLAND | MAK-week 10 mg/m3, JAN2011 | |
Occupational Exposure Limit-THE NETHERLANDS | MAC-TGG 10 mg/m3, 2003 | |
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) | 8H time-weighted average 15 mg/m3, total dust | CFRGBR 29,1926.55,1994 |
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) | 8H time-weighted average 5 mg/m3, respirable fraction | CFRGBR 29,1926.55,1994 |
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) | 8H time-weighted average 15 mg/m3, total dust | CFRGBR 29,1910.1000,1994 |
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) | 8H time-weighted average 5 mg/m3, respirable fraction | CFRGBR 29,1910.1000,1994 |
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) | 8H time-weighted average 15 mg/m3, total dust | CFRGBR 29,1915.1000,1993 |
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) | 8H time-weighted average 5 mg/m3, respirable fraction | CFRGBR 29,1915.1000,1993 |
NIOSH Documentation and Surveillance
Organization | Standard | Reference |
---|---|---|
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO THE CHEMICAL, respirable fraction-air | 10H time-weighted average 5 mg/m3 | NIOSH* DHHS #95-121,1995 |
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO THE CHEMICAL-air | 10H time-weighted average 10 mg/m3;short term exposure limit 20 mg/m3 | NIOSH* DHHS #95-121,1995 |
National Occupational Exposure Survey 1983 | Hazard Code X3196; Number of Industries 1; Total Number of Facilities 12; Number of Occupations 3; Total Number of Employees Exposed 399 |
Status in Federal Agencies
Organization | Reference |
---|---|
EPA TSCA Section 8(b) CHEMICAL INVENTORY | |
On EPA IRIS database |
Page last reviewed: November 16, 2018
Content
source: National Institute for Occupational Safety and Health