Pentaborane(9)

RTECS #

RY8925000

CAS #

19624-22-7
See: NMAM or OSHA Methods

Updated

September 2013

Molecular Weight

63.14

Molecular Formula

B₅H₉

Synonyms

Nonahydropentaborane
Pentaborane
Pentaborane (ACGIH:OSHA)

Acute Toxicity Data and References

Route/Organism	Dose	Effect	Reference
inhalation/Dog	lethal concentration (50 percent kill): 92 mg/m³/15M	Behavioral: Tremor Behavioral: Convulsions or effect on seizure threshold Behavioral: Ataxia	JPETAB 145,382,1964
inhalation/monkey	lethal concentration (50 percent kill): 640 mg/m³/2M	Behavioral: Tremor Behavioral: Convulsions or effect on seizure threshold Behavioral: Ataxia	JPETAB 145,382,1964
inhalation/mouse	lethal concentration (50 percent kill): 0.017 gm/m³/2H		TPKVAL 9,7,1967
inhalation/mouse	lethal concentration (50 percent kill): 6.8 ppm/2H		TPKVAL 9,7,1967
inhalation/mouse	lethal concentration (50 percent kill): 3400 ppb/4H		AIHAAP 19,46,1958
inhalation/rat	lethal concentration (50 percent kill): 18 mg/m³/4H		VCVN1* -,199,1988
inhalation/rat	lowest published toxic concentration: 18 mg/m³/30M	Brain and Coverings: Other degenerative changes	VCVN1* -,199,1988
inhalation/rat	lethal concentration (50 percent kill): 6 ppm/4H		AIHAAP 19,46,1958
intraperitoneal/Dog	lowest published lethal dose: 15800 µg/kg	Peripheral Nerve and Sensation: Spastic paralysis with/without sensory change Behavioral: Tremor Behavioral: Coma	STGNBT -,191,1999
intraperitoneal/rat	lethal dose (50 percent kill): 11100 µg/kg		14KTAK -,693,1964

Other Multiple Dose Data and References

Route/Organism	Dose	Effect	Reference
inhalation/Dog	lowest published toxic concentration: 3700 ppb/1H/3D- intermittent	Behavioral: Convulsions or effect on seizure threshold Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field	TXAPA9 6,121,1964
inhalation/Dog	lowest published toxic concentration: 2.6 mg/m³/4W- intermittent	Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field	VCVN1* -,199,1988
inhalation/hamster	lowest published toxic concentration: 2.6 mg/m³/4W- intermittent	Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field	VCVN1* -,199,1988
inhalation/mouse	lowest published toxic concentration: 3700 ppb/1H/4D- intermittent	Behavioral: Convulsions or effect on seizure threshold Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field	TXAPA9 6,121,1964
inhalation/rabbit	lowest published toxic concentration: 2.6 mg/m³/4W- intermittent	Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field	VCVN1* -,199,1988
inhalation/rat	lowest published toxic concentration: 2.6 mg/m³/4W- intermittent	Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field	VCVN1* -,199,1988
inhalation/rat	lowest published toxic concentration: 67 mg/m³/5M/5D- intermittent	Behavioral: Tetany Eye: Miosis (pupilliary constriction) Eye: Conjunctiva irritation	VCVN1* -,199,1988
inhalation/rat	lowest published toxic concentration: 30 mg/m³/5D- intermittent	Behavioral: Tetany Eye: Miosis (pupilliary constriction) Eye: Conjunctiva irritation	VCVN1* -,199,1988
inhalation/rat	lowest published toxic concentration: 7.8 mg/m³/60M/5D- intermittent	Behavioral: Tetany Eye: Miosis (pupilliary constriction) Eye: Conjunctiva irritation	VCVN1* -,199,1988

Reviews

Organization	Standard	Reference
American Conference of Governmental Industrial Hygienists (ACGIH)	Threshold Limit Value-time-weighted average 0.005 ppm;short term exposure limit 0.015 ppm	DTLVS* TLV/BEI,2013

Standards and Regulations

Organization	Standard	Reference
Mine Safety and Health Administration (MSHA) STANDARD-air	time-weighted average 0.005 ppm (0.01 mg/m³)	DTLVS* 3,197,1971
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIA	time-weighted average 0.005 ppm (0.013 mg/m³), short term exposure limit 0.015 ppm (0.039 mg/m³), JUL2008
Occupational Exposure Limit-AUSTRIA	MAK-TMW 0.005 ppm (0.01 mg/m³);KZW 0.01 ppm (0.02 mg/m³), 2007
Occupational Exposure Limit-BELGIUM	time-weighted average 0.005 ppm (0.013 mg/m³), MAR2002
Occupational Exposure Limit-BELGIUM	short term exposure limit 0.015 ppm (0.04 mg/m³), MAR2002
Occupational Exposure Limit-DENMARK	time-weighted average 0.005 ppm (0.01 mg/m³), MAY2011
Occupational Exposure Limit-FINLAND	time-weighted average 0.005 ppm (0.014 mg/m³), short term exposure limit 0.015 ppm (0.041 mg/m³), NOV2011
Occupational Exposure Limit-FRANCE	VME 0.005 ppm (0.01 mg/m³), FEB2006
Occupational Exposure Limit-GERMANY	MAK 0.005 ppm (0.013 mg/m³), 2011
Occupational Exposure Limit-ICELAND	time-weighted average 0.005 ppm (0.01 mg/m³), NOV2011
Occupational Exposure Limit-KOREA	time-weighted average 0.005 ppm (0.01 mg/m³), short term exposure limit 0.015 ppm (0.03 mg/m³), 2006
Occupational Exposure Limit-MEXICO	time-weighted average 0.005 ppm (0.01 mg/m³);short term exposure limit 0.015 ppm, 2004
Occupational Exposure Limit-NEW ZEALAND	time-weighted average 0.005 ppm (0.013 mg/m³), JAN2002
Occupational Exposure Limit-PERU	time-weighted average 0,005 ppm (0,013 mg/m³); short term exposure limit 0,015 ppm (0,039 mg/m³), JUL2005
Occupational Exposure Limit-SWITZERLAND	MAK-week 0.005 ppm (0.01 mg/m³), KZG-week 0.01 ppm (0.02 mg/m³), JAN2011
Occupational Exposure Limit-THE NETHERLANDS	MAC-TGG 0.01 mg/m³, 2003
Occupational Exposure Limit-THE PHILIPPINES	time-weighted average 0.005 ppm (0.01 mg/m³), JAN1993
Occupational Exposure Limit-TURKEY	time-weighted average 0.01 mg/m³, JAN1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)	8H time-weighted average 0.005 ppm (0.01 mg/m³)	CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)	8H time-weighted average 0.005 ppm (0.01 mg/m³)	CFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)	8H time-weighted average 0.005 ppm (0.01 mg/m³)	CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)	8H time-weighted average 0.005 ppm (0.01 mg/m³)	CFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

Organization	Standard	Reference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO PENTABORANE-air	10H time-weighted average 0.005 ppm;short term exposure limit 0.015 ppm	NIOSH* DHHS #92-100,1992

Status in Federal Agencies

Organization	Reference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
On EPA IRIS database

Page last reviewed: November 16, 2018

Content source: National Institute for Occupational Safety and Health