Oxygen difluoride
RTECS #
RS2100000
CAS #
Updated
September 2013
Molecular Weight
54.00
Molecular Formula
F2O
Synonyms
Fluorine monoxide
Fluorine oxide
Oxygen difluoride (ACGIH:OSHA)
Oxygen fluoride
Fluorine oxide
Oxygen difluoride (ACGIH:OSHA)
Oxygen fluoride
Reproductive Effects Data and References
| Route/Organism | Dose | Effect | Reference |
|---|---|---|---|
| inhalation/rat | 5 mg/m3 (multigenerations) | Reproductive: Specific developmental abnormalities: Blood and lymphatic systems (including spleen and marrow) | VCVN5* -,359,1989 |
Acute Toxicity Data and References
| Route/Organism | Dose | Effect | Reference |
|---|---|---|---|
| inhalation/cat | Lowest published lethal concentration: 71 mg/m3/2H | Peripheral Nerve and Sensation: Spastic paralysis with/without sensory change Lung, Thorax, or Respiration: Fibrosis, focal (pneumoconiosis) Lung, Thorax, or Respiration: Acute pulmonary edema | STGNBT -,232,1999 |
| inhalation/Dog | lethal concentration (50 percent kill): 26 ppm/1H | Lung, Thorax, or Respiration: Acute pulmonary edema Lung, Thorax, or Respiration: Other changes | AMRL** TR-70-77,1970 |
| inhalation/human | lowest published toxic concentration: 500 ppb | Lung, Thorax, or Respiration: Chronic pulmonary edema or congestion | 34ZIAG -,444,1969 |
| inhalation/mammal (species unspecified) | lethal concentration (50 percent kill): 480 mg/m3/5M | VCVN5* -,359,1989 | |
| inhalation/monkey | lethal concentration (50 percent kill): 26 ppm/1H | Behavioral: Muscle weakness Lung, Thorax, or Respiration: Chronic pulmonary edema or congestion Gastrointestinal: Nausea or vomiting | AMRL** TR-70-77,1970 |
| inhalation/mouse | lethal concentration (50 percent kill): 1500 ppb/1H | Lung, Thorax, or Respiration: Acute pulmonary edema Lung, Thorax, or Respiration: Other changes | AMRL** TR-70-77,1970 |
| inhalation/rat | lethal concentration (50 percent kill): 2600 ppb/1H | Lung, Thorax, or Respiration: Acute pulmonary edema Lung, Thorax, or Respiration: Other changes | AMRL** TR-70-77,1970 |
Reviews
| Organization | Standard | Reference |
|---|---|---|
| American Conference of Governmental Industrial Hygienists (ACGIH) | Threshold Limit Value-ceiling concentration 0.05 ppm | DTLVS* TLV/BEI,2013 |
Standards and Regulations
| Organization | Standard | Reference |
|---|---|---|
| Mine Safety and Health Administration (MSHA) STANDARD-air | time-weighted average 0.05 ppm (0.1 mg/m3) | DTLVS* 3,193,1971 |
| Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV | ||
| Occupational Exposure Limit-ARAB Republic of Egypt | time-weighted average 0.05 ppm (0.1 mg/m3), JAN1993 | |
| Occupational Exposure Limit-AUSTRALIA | ceiling concentration 0.05 ppm (0.11 mg/m3), JUL2008 | |
| Occupational Exposure Limit-AUSTRALIA | time-weighted average 2.5 mg(F)/m3, JUL2008 | |
| Occupational Exposure Limit-BELGIUM | short term exposure limit 0.05 ppm (0.11 mg/m3), MAR2002 | |
| Occupational Exposure Limit-DENMARK | ceiling concentration 0.05 ppm (0.1 mg/m3), MAY2011 | |
| Occupational Exposure Limit-FINLAND | short term exposure limit 0.05 ppm (0.11 mg/m3), NOV2011 | |
| Occupational Exposure Limit-ICELAND | short term exposure limit 0.05 ppm (0.1 mg/m3), NOV2011 | |
| Occupational Exposure Limit-KOREA | ceiling concentration 0.05 ppm (0.1 mg/m3), 2006 | |
| Occupational Exposure Limit-MEXICO | peak 0.05 ppm (0.1 mg/m3), 2004 | |
| Occupational Exposure Limit-MEXICO | time-weighted average 2.5 mg(F)/m3, 2004 | |
| Occupational Exposure Limit-NEW ZEALAND | ceiling concentration 0.05 ppm (0.11 mg/m3), JAN2002 | |
| Occupational Exposure Limit-NEW ZEALAND | time-weighted average 2.5 mg(F)/m3, JAN2002 | |
| Occupational Exposure Limit-NORWAY | time-weighted average 0.05 ppm (0.1 mg/m3), JAN1999 | |
| Occupational Exposure Limit-PERU | short term exposure limit 0.05 ppm (0.11 mg/m3), JUL2005 | |
| Occupational Exposure Limit-POLAND | MAC(time-weighted average) 1 mg(HF)/m3, MAC(short term exposure limit) 3 mg(HF)/m3, JAN1999 | |
| Occupational Exposure Limit-SWITZERLAND | MAK-week 0.05 ppm (0.1 mg/m3), JAN2011 | |
| Occupational Exposure Limit-THE NETHERLANDS | MAC-C 0.1 mg/m3, 2003 | |
| Occupational Exposure Limit-THE PHILIPPINES | time-weighted average 0.05 ppm (0.1 mg/m3), JAN1993 | |
| Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) | 8H time-weighted average 0.05 ppm (0.1 mg/m3) | CFRGBR 29,1926.55,1994 |
| Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) | 8H time-weighted average 0.05 ppm (0.1 mg/m3) | CFRGBR 41,50-204.50,1994 |
| Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) | 8H time-weighted average 0.05 ppm (0.1 mg/m3) | CFRGBR 29,1910.1000,1994 |
| Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) | 8H time-weighted average 0.05 ppm (0.1 mg/m3) | CFRGBR 29,1915.1000,1993 |
NIOSH Documentation and Surveillance
| Organization | Standard | Reference |
|---|---|---|
| National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO OXYGEN DIFLUORIDE-air | ceiling concentration 0.05 ppm | NIOSH* DHHS #92-100,1992 |
Page last reviewed: November 16, 2018
Content
source: National Institute for Occupational Safety and Health