Methylamine, m-phenylenebis-

RTECS #

PF8970000

CAS #

1477-55-0
See: NMAM or OSHA Methods

Updated

September 2013

Molecular Weight

136.22

Molecular Formula

C₈H₁₂N₂

Synonyms

1,3-Benzenedimethanamine
1,3-Bis(aminomethyl)benzene
1,3-Bis-aminomethylbenzen (Czech)
m-Phenylenebis(methylamine)
MXDA
m-Xylene alpha,alpha'-diamine
m-Xylene alpha,alpha'-diamine (ACGIH)
m-Xylene-alpha,alpha'-diamine
m-Xylylendiamin (Czech)
m-Xylylenediamine

Skin and Eye Irritation and References

Route/Organism	Dose	Effect	Reference
eye /rabbit	50 µg/24H	severe	85JCAE -,447,1986
skin /rabbit	750 µg/24H	severe	85JCAE -,447,1986

Acute Toxicity Data and References

Route/Organism	Dose	Effect	Reference
inhalation/rat	lethal concentration (50 percent kill): 700 ppm/1H	Eye: Lacrimation Lung, Thorax, or Respiration: Respiratory depression	85INA8 5,638,1986
oral/rat	lethal dose (50 percent kill): 930 mg/kg		85INA8 5,638,1986
skin/rabbit	lethal dose (50 percent kill): 2 gm/kg		85INA8 5,638,1986

Reviews

Organization	Standard	Reference
American Conference of Governmental Industrial Hygienists (ACGIH)	Threshold Limit Value-ceiling concentration 0.1 mg/m³ (skin)	DTLVS* TLV/BEI,2013

Standards and Regulations

Organization	Standard	Reference
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIA	ceiling concentration 0.1 mg/m³, JUL2008
Occupational Exposure Limit-AUSTRIA	MAK-TMW 0.1 mg/m³;KZW 0.1 mg/m³, 2007
Occupational Exposure Limit-BELGIUM	short term exposure limit 0.1 mg/m³, Skin, MAR2002
Occupational Exposure Limit-DENMARK	ceiling concentration 0.02 ppm (0.1 mg/m³), skin, MAY2011
Occupational Exposure Limit-FINLAND	ceiling concentration 0.1 mg/m³, skin, NOV2011
Occupational Exposure Limit-FRANCE	VLE 0.1 mg/m³, FEB2006
Occupational Exposure Limit-ICELAND	short term exposure limit 0.02 ppm (0.1 mg/m³), skin, NOV2011
Occupational Exposure Limit-KOREA	ceiling concentration 0.1 mg/m³, skin, 2006
Occupational Exposure Limit-MEXICO	peak 0.1 mg/m³ (skin), 2004
Occupational Exposure Limit-NEW ZEALAND	ceiling concentration 0.1 mg/m³, skin, JAN2002
Occupational Exposure Limit-NORWAY	time-weighted average 0.1 mg/m³, JAN1999
Occupational Exposure Limit-SWITZERLAND	MAK-week 0.1 mg/m³, skin, JAN2011
Occupational Exposure Limit-THE NETHERLANDS	MAC-C 0.1 mg/m³, 2003

NIOSH Documentation and Surveillance

Organization	Standard	Reference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO m-XYLENE-alpha,alpha'-DIAMINE-air	ceiling concentration 0.1 mg/m³ (Sk)	NIOSH* DHHS #92-100,1992
National Occupational Exposure Survey 1983	Hazard Code 84031; Number of Industries 3; Total Number of Facilities 43; Number of Occupations 4; Total Number of Employees Exposed 1005
National Occupational Hazard Survey 1974	Hazard Code 84031; Number of Industries 1; Total Number of Facilities 5; Number of Occupations 2; Total Number of Employees Exposed 15

Status in Federal Agencies

Organization	Reference
EPA TSCA 8(a) PRELIMINARY ASSESSMENT INFORMATION, PROPOSED RULE	FEREAC 47,27009,82
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
OSHA ANALYTICAL METHOD #105

Page last reviewed: November 16, 2018

Content source: National Institute for Occupational Safety and Health