Methane, dimethoxy-
RTECS #
PA8750000
CAS #
Updated
September 2013
Molecular Weight
76.11
Molecular Formula
C3H8O2
Synonyms
Anesthenyl
Bis(methoxy)methane
Dimethoxymethane
Dimethoxymethane (ACGIH:OSHA)
Dimethyl formal
Dioxapentane
Formal
Formaldehyde dimethylacetal
Formaldehyde methyl ketal
Methoxymethyl methyl ether
Methylal
Methylal (ACGIH:OSHA)
Methylene dimethyl ether
Metylal (Polish)
Bis(methoxy)methane
Dimethoxymethane
Dimethoxymethane (ACGIH:OSHA)
Dimethyl formal
Dioxapentane
Formal
Formaldehyde dimethylacetal
Formaldehyde methyl ketal
Methoxymethyl methyl ether
Methylal
Methylal (ACGIH:OSHA)
Methylene dimethyl ether
Metylal (Polish)
Skin and Eye Irritation and References
Route/Organism | Dose | Effect | Reference |
---|---|---|---|
eye /rabbit | 100 µL | moderate | NTIS** OTS0536049 |
Acute Toxicity Data and References
Route/Organism | Dose | Effect | Reference |
---|---|---|---|
inhalation/mouse | lethal concentration (50 percent kill): 57 gm/m3/7H | 85JCAE -,259,1986 | |
inhalation/mouse | lethal concentration (50 percent kill): 57000 mg/m3/7M | VCVGK* -,501,1994 | |
inhalation/rat | lethal concentration (50 percent kill): 15000 ppm | NPIRI* 1,73,1974 | |
intraperitoneal/rat | lowest published lethal dose: 5 gm/kg | NTIS** OTS0524346 | |
oral/rabbit | lethal dose (50 percent kill): 5708 mg/kg | PSEBAA 29,730,1932 | |
oral/rat | lethal dose (50 percent kill): 6653 mg/kg | GISAAA 11,16,1993 | |
skin/rabbit | Lethal dose: >16 mL/kg | Eye: Iritis Lung, Thorax, or Respiration: Other changes Liver: Other changes | NTIS** OTS0536049 |
Other Multiple Dose Data and References
Route/Organism | Dose | Effect | Reference |
---|---|---|---|
inhalation/mouse | lowest published toxic concentration: 35100 mg/m3/7H/22D- intermittent | Behavioral: Ataxia Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field | BJIMAG 8,279,1951 |
oral/rat | lowest published toxic dose: 7078 mg/kg/3D- intermittent | Behavioral: General anesthetic Behavioral: Ataxia Kidney, Ureter, and Bladder: Urine volume increased | IJTOFN 19,179,2000 |
Reviews
Organization | Standard | Reference |
---|---|---|
American Conference of Governmental Industrial Hygienists (ACGIH) | Threshold Limit Value-time-weighted average 1000 ppm | DTLVS* TLV/BEI,2013 |
TOXICOLOGY REVIEW | MUREAV 539,77,2003 |
Standards and Regulations
Organization | Standard | Reference |
---|---|---|
Mine Safety and Health Administration (MSHA) STANDARD-air | time-weighted average 1000 ppm (3100 mg/m3) | DTLVS* 3,154,1971 |
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV; | ||
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV | ||
Occupational Exposure Limit-AUSTRALIA | time-weighted average 1000 ppm (3110 mg/m3), JUL2008 | |
Occupational Exposure Limit-AUSTRIA | MAK-TMW 1000 ppm (3100 mg/m3), 2007 | |
Occupational Exposure Limit-BELGIUM | time-weighted average 1000 ppm (3155 mg/m3), MAR2002 | |
Occupational Exposure Limit-DENMARK | time-weighted average 1000 ppm (3100 mg/m3), MAY2011 | |
Occupational Exposure Limit-FINLAND | time-weighted average 1000 ppm (3200 mg/m3), short term exposure limit 1300 ppm (4100 mg/m3), NOV2011 | |
Occupational Exposure Limit-FRANCE | VME 1000 ppm (3100 mg/m3), FEB2006 | |
Occupational Exposure Limit-GERMANY | MAK 1000 ppm (3200 mg/m3), 2011 | |
Occupational Exposure Limit-ICELAND | time-weighted average 1000 ppm (3100 mg/m3), NOV2011 | |
Occupational Exposure Limit-KOREA | time-weighted average 1000 ppm (3100 mg/m3), 2006 | |
Occupational Exposure Limit-MEXICO | time-weighted average 1000 ppm (3100 mg/m3), 2004 | |
Occupational Exposure Limit-NEW ZEALAND | time-weighted average 1000 ppm (3100 mg/m3), JAN2002 | |
Occupational Exposure Limit-PERU | time-weighted average 1000 ppm (3112 mg/m3), JUL2005 | |
Occupational Exposure Limit-POLAND | MAC(time-weighted average) 1000 mg/m3, MAC(short term exposure limit) 3500 mg/m3, JAN1999 | |
Occupational Exposure Limit-RUSSIA | time-weighted average 10 mg/m3, short term exposure limit 30 mg/m3, JUN2003 | |
Occupational Exposure Limit-SWITZERLAND | MAK-week 1000 ppm (3100 mg/m3), KZG-week 2000 ppm (6200 mg/m3), JAN2011 | |
Occupational Exposure Limit-THE NETHERLANDS | MAC-TGG 3100 mg/m3, 2003 | |
Occupational Exposure Limit-THE PHILIPPINES | time-weighted average 1000 ppm (3100 mg/m3), JAN1993 | |
Occupational Exposure Limit-TURKEY | time-weighted average 1000 ppm (3100 mg/m3), JAN1993 | |
Occupational Exposure Limit-UNITED KINGDOM | time-weighted average 1000 ppm (3160 mg/m3);short term exposure limit 1250 ppm (3950 mg/m3), OCT2007 | |
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) | 8H time-weighted average 1000 ppm (3100 mg/m3) | CFRGBR 29,1926.55,1994 |
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) | 8H time-weighted average 1000 ppm (3100 mg/m3) | CFRGBR 41,50-204.50,1994 |
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) | 8H time-weighted average 1000 ppm (3100 mg/m3) | CFRGBR 29,1910.1000,1994 |
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) | 8H time-weighted average 1000 ppm (3100 mg/m3) | CFRGBR 29,1915.1000,1993 |
NIOSH Documentation and Surveillance
Organization | Standard | Reference |
---|---|---|
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO METHYLAL-air | 10H time-weighted average 1000 ppm | NIOSH* DHHS #92-100,1992 |
National Occupational Exposure Survey 1983 | Hazard Code 26075; Number of Industries 123; Total Number of Facilities 9104; Number of Occupations 70; Total Number of Employees Exposed 156806; Total Number of Female Employees Exposed 21093 | |
National Occupational Hazard Survey 1974 | Hazard Code 26075; Number of Industries 5; Total Number of Facilities 122; Number of Occupations 6; Total Number of Employees Exposed 399 |
Status in Federal Agencies
Page last reviewed: November 16, 2018
Content
source: National Institute for Occupational Safety and Health