Gasoline, natural
RTECS #
LX3300000
CAS #
Updated
July 2016
Molecular Weight
N/R
Molecular Formula
N/R
Synonyms
Automobile regular unleaded gasoline
Gasoline
Gasoline (ACGIH:OSHA)
Natural gasoline
Petrol
Petrol, natural
Gasoline
Gasoline (ACGIH:OSHA)
Natural gasoline
Petrol
Petrol, natural
Skin and Eye Irritation and References
| Route/Organism | Dose | Effect | Reference |
|---|---|---|---|
| eye /human | 140 ppm/8H | mild | JIHTAB 25,225,1943 |
| eye /man | 500 ppm/1H | moderate | AEHLAU 1,548,1960 |
Acute Toxicity Data and References
| Route/Organism | Dose | Effect | Reference |
|---|---|---|---|
| inhalation/guinea pig | lethal concentration (50 percent kill): 300 gm/m3/5M | Lung, Thorax, or Respiration: Dyspnea | NTIS** PB158-508 |
| inhalation/mammal (species unspecified) | Lowest published lethal concentration: 30000 ppm/5M | AEPPAE 138,65,1928 | |
| inhalation/man | lowest published toxic concentration: 900 ppm/1H | Eye: Conjunctiva irritation Behavioral: Hallucinations, distorted perceptions Lung, Thorax, or Respiration: Cough | JIHTAB 25,225,1943 |
| inhalation/mouse | lethal concentration (50 percent kill): 300 gm/m3/5M | NTIS** PB158-508 | |
| inhalation/rat | lethal concentration (50 percent kill): 300 gm/m3/5M | NTIS** PB158-508 | |
| parenteral/man | lowest published toxic dose: 53 mg/kg | Skin: After systemic exposure: Dermatitis, allergic | JTCTDW 21,409,1983/1984 |
Other Multiple Dose Data and References
| Route/Organism | Dose | Effect | Reference |
|---|---|---|---|
| inhalation/rat | lowest published toxic concentration: 3200 ppm/6H/4W- intermittent | Kidney, Ureter, and Bladder: Other changes in urine composition Blood: Pigmented or nucleated red blood cells Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other oxidoreductases | TIHEEC 11,343,1995 |
| inhalation/rat | lowest published toxic concentration: 3 gm/m3/4H/43W- intermittent | Eye: Conjunctiva irritation | VEOFA6 78(1),36,1965 |
| inhalation/rat | lowest published toxic concentration: 500 ppm/4W- intermittent | Brain and Coverings: Other degenerative changes Kidney, Ureter, and Bladder: Other changes in urine composition Kidney, Ureter, and Bladder: Changes in kidney weight | JAPTO* 25,193,2005 |
| inhalation/rat | lowest published toxic concentration: 500 ppm/4W- intermittent | Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol) Blood: Changes in leukocyte (WBC) count Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) | JAPTO* 25,193,2005 |
| inhalation/rat | lowest published toxic concentration: 500 ppm/4W- intermittent | Biochemical: Neurotransmitters or modulators (putative): Dopamine at other sites | JAPTO* 25,193,2005 |
| inhalation/rat | lowest published toxic concentration: 500 ppm/4W- intermittent | Brain and Coverings: Other degenerative changes Cardiac: Changes in heart weight Kidney, Ureter, and Bladder: Other changes in urine composition | JAPTO* 25,193,2005 |
| inhalation/rat | lowest published toxic concentration: 500 ppm/4W- intermittent | Endocrine: Hyperglycemia Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol) Blood: Other changes | JAPTO* 25,193,2005 |
| inhalation/rat | lowest published toxic concentration: 500 ppm/4W- intermittent | Blood: Changes in leukocyte (WBC) count Biochemical: Metabolism (intermediary): Other Biochemical: Neurotransmitters or modulators (putative): Dopamine at other sites | JAPTO* 25,193,2005 |
| oral/rat | lowest published toxic dose: 1500 mg/kg/3D- intermittent | Kidney, Ureter, and Bladder: Other changes in urine composition | JAPTO* 21,461,2001 |
| oral/rat | lowest published toxic dose: 5 mg/kg/2W- intermittent | Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis) Kidney, Ureter, and Bladder: Changes in kidney weight | TOLED5 44,13,1988 |
| unreported route/man | lowest published toxic dose: 16.5 mL/kg/7Y- intermittent | Peripheral Nerve and Sensation: Recording from peripheral motor nerve Behavioral: Tremor | DADEDV 73,183,2004 |
Reviews
| Organization | Standard | Reference |
|---|---|---|
| International Agency for Research on Cancer (IARC) | Cancer Review:Human Inadequate Evidence | IMEMDT 45,159,1989 |
| International Agency for Research on Cancer (IARC) | Cancer Review:Group 2B | IMEMDT 45,159,1989 |
| TOXICOLOGY REVIEW | NEJMAG 342,186,2000 | |
| TOXICOLOGY REVIEW | TOLED5 128,85,2002 | |
| TOXICOLOGY REVIEW | MUREAV 566,209,2004 | |
| TOXICOLOGY REVIEW | MUREAV 613,138,2006 | |
| TOXICOLOGY REVIEW | ENTOX* -,408,2005 | |
| TOXICOLOGY REVIEW | HUTOX* -,577,1996 | |
| TOXICOLOGY REVIEW | AIRMJ* 20,8,2001 | |
| TOXICOLOGY REVIEW | NEUCL* 15,711,1997 | |
| TOXICOLOGY REVIEW | NEUCL* 18,215,2000 | |
| TOXICOLOGY REVIEW | NBREV* 26,81,2002 | |
| TOXICOLOGY REVIEW | NRTXDN 31,603,2010 | |
| TOXICOLOGY REVIEW | MUREAV 728,88,2011 | |
| TOXICOLOGY REVIEW | MUREAV 762,76,2014 | |
| TOXICOLOGY REVIEW | REPTED 58,252,2015 |
Standards and Regulations
| Organization | Standard | Reference |
|---|---|---|
| Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV; | ||
| Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV | ||
| Occupational Exposure Limit-BELGIUM | time-weighted average 300 ppm (903 mg/m3), MAR2002 | |
| Occupational Exposure Limit-BELGIUM | short term exposure limit 500 ppm (1501 mg/m3), MAR2002 | |
| Occupational Exposure Limit-JAPAN | Occupational Exposure Limit 100 ppm (300 mg/m3), 2B carc, MAY2012 | |
| Occupational Exposure Limit-KOREA | time-weighted average 300 ppm (900 mg/m3), short term exposure limit 500 ppm (1500 mg/m3), 2006 | |
| Occupational Exposure Limit-NEW ZEALAND | time-weighted average 300 ppm (890 mg/m3), short term exposure limit 500 ppm (1480 mg/m3), JAN2002 | |
| Occupational Exposure Limit-SWITZERLAND | MAK-week 500 ppm (2000 mg/m3), JAN2011 | |
| Occupational Exposure Limit-TURKEY | time-weighted average 500 ppm (2000 mg/m3), JAN1993 | |
| Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) | see Appendix A3 | CFRGBR 29,1926.55,1994 |
NIOSH Documentation and Surveillance
| Organization | Standard | Reference |
|---|---|---|
| National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO GASOLINE-air | Carcinogen (15 ppm LOQ) | NIOSH* DHHS #92-100,1992 |
| National Occupational Exposure Survey 1983 | Hazard Code X6705; Number of Industries 1; Total Number of Facilities 7; Number of Occupations 2; Total Number of Employees Exposed 70; Total Number of Female Employees Exposed 7 |
Status in Federal Agencies
| Organization | Reference |
|---|---|
| EPA TSCA Section 8(b) CHEMICAL INVENTORY | |
| EPA TSCA Section 8(d) unpublished health/safety studies | |
| EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001 |
Page last reviewed: November 16, 2018
Content
source: National Institute for Occupational Safety and Health