Ethylene glycol, dinitrate
RTECS #
KW5600000
CAS #
Updated
September 2013
Molecular Weight
152.08
Molecular Formula
C2H4N2O6
Synonyms
Dinitroglicol (Italian)
Dinitroglycol
EGDN
Ethanediol dinitrate
Ethylene dinitrate
Ethylene glycol dinitrate (ACGIH:OSHA)
Ethylene nitrate
Ethylenglykoldinitrat (Czech)
Glycol (dinitrate de) (French)
Glycol dinitrate
Glycoldinitraat (Dutch)
Glykoldinitrat (German)
Nitroglycol
Nitroglykol (Czech)
Dinitroglycol
EGDN
Ethanediol dinitrate
Ethylene dinitrate
Ethylene glycol dinitrate (ACGIH:OSHA)
Ethylene nitrate
Ethylenglykoldinitrat (Czech)
Glycol (dinitrate de) (French)
Glycol dinitrate
Glycoldinitraat (Dutch)
Glykoldinitrat (German)
Nitroglycol
Nitroglykol (Czech)
Acute Toxicity Data and References
Route/Organism | Dose | Effect | Reference |
---|---|---|---|
oral/mouse | lethal dose (50 percent kill): 540 mg/kg | Behavioral: Somnolence (general depressed activity) Behavioral: Convulsions or effect on seizure threshold Cardiac: Other changes | STGNBT -,96,1999 |
oral/rat | lethal dose (50 percent kill): 460 mg/kg | Behavioral: Somnolence (general depressed activity) Behavioral: Convulsions or effect on seizure threshold Cardiac: Other changes | STGNBT -,96,1999 |
skin/rat | lethal dose (50 percent kill): 3800 mg/kg | STGNBT -,96,1999 | |
subcutaneous/cat | lowest published lethal dose: 75 mg/kg | Blood: Normocytic anemia | AEPPAE 200,271,1942 |
subcutaneous/rabbit | lowest published lethal dose: 300 mg/kg | Vascular: Other changes Blood: Normocytic anemia | AEPPAE 200,271,1942 |
Other Multiple Dose Data and References
Route/Organism | Dose | Effect | Reference |
---|---|---|---|
inhalation/rat | lowest published toxic concentration: 10 mg/m3/17W- intermittent | Cardiac: Other changes Kidney, Ureter, and Bladder: Other changes Blood: Pigmented or nucleated red blood cells | STGNBT -,96,1999 |
oral/rat | lowest published toxic dose: 3067 mg/kg/20D- intermittent | Kidney, Ureter, and Bladder: Changes in kidney weight Blood: Other changes Nutritional and Gross Metabolic: Weight loss or decreased weight gain | STGNBT -,96,1999 |
subcutaneous/rat | lowest published toxic dose: 1 gm/kg/10D- intermittent | Behavioral: Tolerance Biochemical: Neurotransmitters or modulators (putative): Catecholamine levels in CNS | PHTOEH 61,172,1987 |
Reviews
Organization | Standard | Reference |
---|---|---|
American Conference of Governmental Industrial Hygienists (ACGIH) | Threshold Limit Value-time-weighted average 0.05 ppm (skin) | DTLVS* TLV/BEI,2013 |
TOXICOLOGY REVIEW | NTIS** AD778-725 | |
TOXICOLOGY REVIEW | AJMEAZ 38,409,1965 |
Standards and Regulations
Organization | Standard | Reference |
---|---|---|
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV; | ||
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV | ||
Occupational Exposure Limit-AUSTRALIA | time-weighted average 0.05 ppm (0.31 mg/m3), JUL2008 | |
Occupational Exposure Limit-AUSTRIA | MAK-TMW 0.05 ppm (0.3 mg/m3);KZW 0.2 ppm (1.2 mg/m3), skin, 2007 | |
Occupational Exposure Limit-BELGIUM | time-weighted average 0.05 ppm (0.31 mg/m3), Skin, MAR2002 | |
Occupational Exposure Limit-DENMARK | ceiling concentration 0.02 ppm (0.12 mg/m3), skin, MAY2011 | |
Occupational Exposure Limit-FINLAND | time-weighted average 0.03 ppm (0.2 mg/m3), short term exposure limit 0.1 ppm (0.6 mg/m3), skin, NOV2011 | |
Occupational Exposure Limit-FRANCE | VME 0.17 ppm (1 mg/m3), Skin, FEB2006 | |
Occupational Exposure Limit-GERMANY | MAK 0.05 ppm (0.32 mg/m3), skin, 2011 | |
Occupational Exposure Limit-ICELAND | short term exposure limit 0.02 ppm (0.12 mg/m3), skin, NOV2011 | |
Occupational Exposure Limit-JAPAN | Occupational Exposure Limit 0.05 ppm (0.31 mg/m3), skin, MAY2012 | |
Occupational Exposure Limit-KOREA | time-weighted average 0.05 ppm (0.3 mg/m3), skin, 2006 | |
Occupational Exposure Limit-KOREA | time-weighted average 0.5 ppm (1.2 mg/m3), 2006 | |
Occupational Exposure Limit-MEXICO | time-weighted average 0.05 ppm (0.3 mg/m3);short term exposure limit 0.1 ppm (skin), 2004 | |
Occupational Exposure Limit-NEW ZEALAND | time-weighted average 0.05 ppm (0.31 mg/m3), skin, JAN2002 | |
Occupational Exposure Limit-NORWAY | time-weighted average 0.03 ppm (0.18 mg/m3), JAN1999 | |
Occupational Exposure Limit-PERU | time-weighted average 0,05 ppm (0,3 mg/m3), JUL2005 | |
Occupational Exposure Limit-POLAND | time-weighted average 0.3 mg/m3, short term exposure limit 0.4 mg/m3, JAN1999 | |
Occupational Exposure Limit-RUSSIA | time-weighted average 0.05 mg/m3, JUN2003 | |
Occupational Exposure Limit-SWEDEN | time-weighted average 0.03 ppm (0.2 mg/m3);short term exposure limit 0.1 ppm (0.6 mg/m3), Skin, JUN2005 | |
Occupational Exposure Limit-SWITZERLAND | ceiling concentration 0.05 ppm (0.3 mg/m3), skin, JAN2011 | |
Occupational Exposure Limit-THAILAND | time-weighted average 0.2 ppm (1 mg/m3), JAN1993 | |
Occupational Exposure Limit-THE NETHERLANDS | MAC-TGG 0.3 mg/m3, Skin, 2003 | |
Occupational Exposure Limit-THE PHILIPPINES | time-weighted average 0.2 ppm (1.2 mg/m3), Skin, JAN1993 | |
Occupational Exposure Limit-TURKEY | time-weighted average 0.2 ppm (1 mg/m3), Skin, JAN1993 | |
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) | ceiling concentration 0.2 ppm (1 mg/m3) (skin) | CFRGBR 29,1926.55,1994 |
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) | ceiling concentration 0.2 ppm (1 mg/m3) (skin) | CFRGBR 41,50-204.50,1994 |
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) | ceiling concentration 0.2 ppm (1 mg/m3) (skin) | CFRGBR 29,1910.1000,1994 |
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) | ceiling concentration 0.2 ppm (1 mg/m3) (skin) | CFRGBR 29,1915.1000,1993 |
NIOSH Documentation and Surveillance
Organization | Standard | Reference |
---|---|---|
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO ETHYLENE GLYCOL DINITRATE-air | short term exposure limit 0.1 mg/m3 (Sk) | NIOSH* DHHS #92-100,1992 |
Status in Federal Agencies
Page last reviewed: November 16, 2018
Content
source: National Institute for Occupational Safety and Health