Coal-tar pitch
RTECS #
GF8655000
CAS #
Updated
March 2018
Molecular Weight
N/R
Molecular Formula
N/R
Synonyms
Coal tar pitch volatiles (ACGIH:OSHA)
Pitch
Pitch, coal tar
Pitch
Pitch, coal tar
Tumorigenic Data and References
| Route/Organism | Dose | Effect | Reference |
|---|---|---|---|
| intratracheal/rat | lowest published toxic dose: 1 gm/kg/10W- intermittent | Tumorigenic: Carcinogenic by RTECS criteria Lung, Thorax, or Respiration: Tumors | CRNGDP 13,233,1992 |
| skin/mouse | lowest published toxic dose: 36 gm/kg/18W- intermittent | Tumorigenic: Carcinogenic by RTECS criteria Skin and Appendages: Tumors Tumorigenic: Tumors at site of application | AJIMD8 2,59,1981 |
| skin/mouse | toxic dose: 4200 mg/kg/31W- intermittent | Tumorigenic: Neoplastic by RTECS criteria Skin and Appendages: Tumors Tumorigenic: Tumors at site of application | TXAPA9 18,41,1971 |
| skin/mouse | toxic dose: 82 gm/kg/52W- intermittent | Tumorigenic: Carcinogenic by RTECS criteria Lung, Thorax, or Respiration: Tumors Skin and Appendages: Tumors | HYSAAV 33(4-6),180,1968 |
Other Multiple Dose Data and References
| Route/Organism | Dose | Effect | Reference |
|---|---|---|---|
| inhalation/guinea pig | lowest published toxic concentration: 880 mg/m3/7D- continuous | Eye: Conjunctiva irritation Behavioral: Somnolence (general depressed activity) Nutritional and Gross Metabolic: Weight loss or decreased weight gain | VCVPS* -,146,1998 |
| inhalation/mouse | lowest published toxic concentration: 50 mg/m3/4W- continuous | Lung, Thorax, or Respiration: Structural or functional change in trachea or bronchi Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field | VCVPS* -,146,1998 |
| inhalation/rat | lowest published toxic concentration: 10 mg/m3/4H/8W- intermittent | Blood: Changes in erythrocyte (RBC) count Biochemical: Metabolism (intermediary): Plasma proteins not involving coagulation | VCVPS* -,131,1998 |
| inhalation/rat | lowest published toxic concentration: 10 mg/m3/4H/17W- intermittent | Peripheral Nerve and Sensation: Recording from peripheral motor nerve Blood: Normocytic anemia Biochemical: Metabolism (intermediary): Amino acids (including renal excretion) | VCVPS* -,131,1998 |
Reviews
| Organization | Standard | Reference |
|---|---|---|
| American Conference of Governmental Industrial Hygienists (ACGIH) | Threshold Limit Value-time-weighted average 0.2 mg/m3 | DTLVS* TLV/BEI,2013 |
| American Conference of Governmental Industrial Hygienists (ACGIH) | Threshold Limit Value-Confirmed human carcinogen | DTLVS* TLV/BEI,2013 |
| International Agency for Research on Cancer (IARC) | Cancer Review:Animal Sufficient Evidence | IMEMDT 35,83,1985 |
| International Agency for Research on Cancer (IARC) | Cancer Review:Human Sufficient Evidence | IMEMDT 35,83,1985 |
| International Agency for Research on Cancer (IARC) | Cancer Review:Human Sufficient Evidence | IMEMDT 3,22,1973 |
| International Agency for Research on Cancer (IARC) | Cancer Review:Animal Sufficient Evidence | IMEMDT 100F,165,2012 |
| International Agency for Research on Cancer (IARC) | Cancer Review:Human Sufficient Evidence | IMEMDT 100F,165,2012 |
| International Agency for Research on Cancer (IARC) | Cancer Review:Group 1 | IMSUDL 7,174,1987 |
| International Agency for Research on Cancer (IARC) | Cancer Review:Group 1 | IMEMDT 100F,165,2012 |
| TOXICOLOGY REVIEW | JIDHAN 5,462,1924 | |
| TOXICOLOGY REVIEW | PAASAH 54,171,1959 |
Standards and Regulations
| Organization | Standard | Reference |
|---|---|---|
| Mine Safety and Health Administration (MSHA) STANDARD-air | time-weighted average 0.2 mg/m3 | DTLVS* 3,57,1971 |
| Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV; | ||
| Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV | ||
| Occupational Exposure Limit-AUSTRALIA | time-weighted average 0.2 mg/m3, JUL2008 | |
| Occupational Exposure Limit-BELGIUM | time-weighted average 0.2 mg/m3, Carcinogen, MAR2002 | |
| Occupational Exposure Limit-DENMARK | time-weighted average 0.2 mg/m3, carc, MAY2011 | |
| Occupational Exposure Limit-FRANCE | VME 0.2 mg/m3, FEB2006 | |
| Occupational Exposure Limit-ICELAND | time-weighted average 0.2 mg/m3, carc, NOV2011 | |
| Occupational Exposure Limit-JAPAN | 1 carc, MAY2012 | |
| Occupational Exposure Limit-MEXICO | time-weighted average 0.02 mg/m3;short term exposure limit 0.015 ppm (0.03 mg/m3), 2004 | |
| Occupational Exposure Limit-PERU | time-weighted average 0.2 mg/m3, JUL2005 | |
| Occupational Exposure Limit-SWITZERLAND | MAK-week 0.2 mg/m3, carc 2, inhal, JAN2011 | |
| Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) | 8H time-weighted average 0.2 mg/m3 | CFRGBR 29,1926.55,1994 |
| Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) | 8H time-weighted average 0.2 mg/m3 | CFRGBR 41,50-204.50,1994 |
| Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) | 8H time-weighted average 0.2 mg/m3 | CFRGBR 29,1910.1000,1994 |
| Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) | 8H time-weighted average 0.2 mg/m3 | CFRGBR 29,1915.1000,1993 |
NIOSH Documentation and Surveillance
| Organization | Standard | Reference |
|---|---|---|
| National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO COAL TAR PRODUCTS-air | 10H time-weighted average 0.1 mg/m3 CHE fraction | MMWR** 37(S-7),9,1988 |
| National Occupational Exposure Survey 1983 | Hazard Code T0535; Number of Industries 20; Total Number of Facilities 1235; Number of Occupations 22; Total Number of Employees Exposed 19021; Total Number of Female Employees Exposed 98 | |
| National Occupational Hazard Survey 1974 | Hazard Code T0535; Number of Industries 4; Total Number of Facilities 190; Number of Occupations 6; Total Number of Employees Exposed 1354 |
Status in Federal Agencies
Page last reviewed: November 16, 2018
Content
source: National Institute for Occupational Safety and Health