Funding for Long-Acting Antiretroviral Therapies in Priority Populations Living with HIV Who Are Disproportionately Affected

Funding overview

Creating equitable access to HIV treatment and care for people with HIV (PWH) includes the successful use of new and emerging treatments. Long-acting antiretroviral therapies (LA-ART) offer convenience and reduced stigma compared to daily oral treatment.

Inequities in HIV include the disproportionate rate of HIV among cisgender Black women with HIV (CgBWH). CgBWH account for nearly 60% of new HIV infections in U.S. women, despite making up less than 15% of the female population. The following social determinants of health (SDOH) cause CgBWH to bear the highest burden of HIV infection among U.S. women:

• Racism
• Poverty
• Stigma
• Unequal access to health care
• Housing and educational inequities

Because of the disproportionate rate of infection and related SDOH, this notice of funding opportunity (NOFO) focuses on the CgBWH population.

This NOFO uses an exploratory qualitative approach as a unique source of information about LA-ART from the perspectives and experiences of CgBWH. It includes:

• Barriers and facilitators to uptake and use.
• Individual and systemic supports needed to deliver this therapy.

Qualitative research designs produce information about decision-making and circumstances for LA-ART that quantitative data may not show. Interviews and focus groups should include information on LA-ART delivery methods that are currently approved or in clinical trials, such as:

• Administration.
• ART class.
• Frequency of dosing.
• Safety.
• Efficacy.
• Adverse drug reactions.

The findings of this research will:

• Inform strategies to strengthen uptake and adherence to ART.
• Reduce existing disparities in HIV viral suppression among CgBWH.

Important dates

• Letter of Intent due date: Monday, February 20, 2023, 11:59 PM EST
• Application due date: Friday, March 17, 2023, 11:59 PM EST

Initiative priorities

This NOFO supports the Ending the HIV Epidemic in the U.S. (EHE) initiative Treat pillar. Specifically, the EHE plan lists CgBWH as a priority population to focus on to reach National HIV/AIDS Strategy (NHAS) goals. This NOFO supports formative research on acceptance and perceived barriers and facilitators of using current and future LA-ART among CgBWH.

Activities and progress

This NOFO announcement is available at www.grants.gov. Select the Search Grants tab and enter RFA-PS23-003 into the Basic Search Criteria, Opportunity Number box. Select the checkbox next to Archived.

To learn more about the CDC application process, visit the How to Apply for Grants webpage.

Recipients

Eligible applicants

• Native American tribal governments (federally recognized).
• Public housing authorities/Indian housing authorities.
• Nonprofits that have a 501c3 status with the IRS, other than institutions of higher education.
• Independent school districts.
• Private institutions of higher education.
• State governments.
• Nonprofits that do not have a 501c3 status with the IRS, other than institutions of higher education.
• Public and state-controlled institutions of higher education.
• Native American tribal organizations (other than federally recognized tribal governments).
• For profit organizations other than small businesses.
• County governments.
• Special district governments.
• Small businesses.
• City or township governments.

Contacts

Jocelyn Patterson Mosley, MPH, MA
Scientific/Research Contact
jpatterson@cdc.gov
404-639-6437