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West Nile Virus Activity --- United States, November 9--16, 2004

During November 9--16, a total of 31 cases of human West Nile virus (WNV) illness were reported from eight states (Arizona, Georgia, Maryland, Michigan, Missouri, New York, Pennsylvania, and Texas).

During 2004, 40 states and the District of Columbia (DC) have reported 2,313 cases of human WNV illness to CDC through ArboNET (Figure and Table). Of these, 737 (32%) cases were reported in California, 390 (17%) in Arizona, and 276 (12%) in Colorado. A total of 1,339 (59%) of the 2,282 cases for which such data were available occurred in males; the median age of patients was 52 years (range: 1 month--99 years). Date of illness onset ranged from April 23 to November 4; a total of 79 cases were fatal.

A total of 192 presumptive West Nile viremic blood donors (PVDs) have been reported to ArboNET in 2004. Of these, 68 (35%) were reported in California; 35 (18%) in Arizona; 16 in Texas; 15 in New Mexico; seven in Colorado; six each in Louisiana and Oklahoma; five in Nevada; four in Georgia and Iowa; three each in Florida, Michigan, and South Dakota; two each in Minnesota, Mississippi, Missouri, and Wisconsin; and one each in Delaware, Kentucky, Maryland, Nebraska, New Jersey, New York, North Dakota, Oregon, and Pennsylvania. Of the 192 PVDs, three persons aged 35, 69, and 77 years subsequently had neuroinvasive illness, and 55 persons (median age: 52 years; range: 17--73 years) subsequently had West Nile fever.

In addition, 5,660 dead corvids and 1,414 other dead birds with WNV infection have been reported from 46 states and New York City during 2004. WNV infections have been reported in horses in 37 states; one bat in Wisconsin; nine dogs in Nevada, New Mexico, and Wisconsin; seven squirrels in Arizona and Wyoming; and 14 unidentified animal species in nine states (Arizona, Idaho, Illinois, Iowa, Kentucky, Missouri, Nevada, New York, and South Carolina). WNV seroconversions have been reported in 1,429 sentinel chicken flocks in 14 states (Alabama, Arizona, Arkansas, California, Delaware, Florida, Iowa, Louisiana, Nebraska, Nevada, North Carolina, Pennsylvania, South Dakota, and Utah) and in 31 wild hatchling birds in Missouri and Ohio. Four seropositive sentinel horses were reported in Minnesota and Puerto Rico. A total of 8,263 WNV-positive mosquito pools have been reported in 38 states, DC, and New York City.

Additional information about national WNV activity is available from CDC at http://www.cdc.gov/ncidod/dvbid/westnile/index.htm and at http://westnilemaps.usgs.gov.

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