What to know
The team at UCSF plans to combine whole-genome sequencing for SARS-CoV-2 variants with host transcriptome and antibody analyses to develop models for predicting poor outcomes of SARS-CoV-2 infection and likelihood of vaccine breakthrough or re-infection.
Findings on SARS-CoV-2 surveillance and investigations
This project provided a systems-level view of immune responses and tissue damage in COVID-19 and MIS-C which could inform future development of new disease biomarkers.1
Awarded in 2022, this project is still in progress.